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Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism.
Lagor WR, Johnston JC, Lock M, Vandenberghe LH, Rader DJ. Lagor WR, et al. Among authors: johnston jc. Methods Mol Biol. 2013;1027:273-307. doi: 10.1007/978-1-60327-369-5_13. Methods Mol Biol. 2013. PMID: 23912992
Targeting adipose tissue via systemic gene therapy.
O'Neill SM, Hinkle C, Chen SJ, Sandhu A, Hovhannisyan R, Stephan S, Lagor WR, Ahima RS, Johnston JC, Reilly MP. O'Neill SM, et al. Among authors: johnston jc. Gene Ther. 2014 Jul;21(7):653-61. doi: 10.1038/gt.2014.38. Epub 2014 May 15. Gene Ther. 2014. PMID: 24830434 Free PMC article.
The Gene Therapy Resource Program: A Decade of Dedication to Translational Research by the National Heart, Lung, and Blood Institute.
Flotte TR, Daniels E, Benson J, Bevett-Rose JM, Cornetta K, Diggins M, Johnston J, Sepelak S, van der Loo JCM, Wilson JM, McDonald CL. Flotte TR, et al. Among authors: johnston j. Hum Gene Ther Clin Dev. 2017 Dec;28(4):178-186. doi: 10.1089/humc.2017.170. Epub 2017 Nov 27. Hum Gene Ther Clin Dev. 2017. PMID: 29130351 Free PMC article.
Enhancing the utility of adeno-associated virus gene transfer through inducible tissue-specific expression.
Chen SJ, Johnston J, Sandhu A, Bish LT, Hovhannisyan R, Jno-Charles O, Sweeney HL, Wilson JM. Chen SJ, et al. Among authors: johnston j. Hum Gene Ther Methods. 2013 Aug;24(4):270-8. doi: 10.1089/hgtb.2012.129. Hum Gene Ther Methods. 2013. PMID: 23895325 Free PMC article.
Specific AAV serotypes stably transduce primary hippocampal and cortical cultures with high efficiency and low toxicity.
Royo NC, Vandenberghe LH, Ma JY, Hauspurg A, Yu L, Maronski M, Johnston J, Dichter MA, Wilson JM, Watson DJ. Royo NC, et al. Among authors: johnston j. Brain Res. 2008 Jan 23;1190:15-22. doi: 10.1016/j.brainres.2007.11.015. Epub 2007 Nov 17. Brain Res. 2008. PMID: 18054899 Free PMC article.
A comparative analysis of novel fluorescent proteins as reporters for gene transfer studies.
Bell P, Vandenberghe LH, Wu D, Johnston J, Limberis M, Wilson JM. Bell P, et al. Among authors: johnston j. J Histochem Cytochem. 2007 Sep;55(9):931-9. doi: 10.1369/jhc.7A7180.2007. Epub 2007 May 17. J Histochem Cytochem. 2007. PMID: 17510373
Heparin binding directs activation of T cells against adeno-associated virus serotype 2 capsid.
Vandenberghe LH, Wang L, Somanathan S, Zhi Y, Figueredo J, Calcedo R, Sanmiguel J, Desai RA, Chen CS, Johnston J, Grant RL, Gao G, Wilson JM. Vandenberghe LH, et al. Among authors: johnston j. Nat Med. 2006 Aug;12(8):967-71. doi: 10.1038/nm1445. Epub 2006 Jul 16. Nat Med. 2006. PMID: 16845388
High-level transgene expression in nonhuman primate liver with novel adeno-associated virus serotypes containing self-complementary genomes.
Gao GP, Lu Y, Sun X, Johnston J, Calcedo R, Grant R, Wilson JM. Gao GP, et al. Among authors: johnston j. J Virol. 2006 Jun;80(12):6192-4. doi: 10.1128/JVI.00526-06. J Virol. 2006. PMID: 16731960 Free PMC article.
Novel adeno-associated viruses from rhesus monkeys as vectors for human gene therapy.
Gao GP, Alvira MR, Wang L, Calcedo R, Johnston J, Wilson JM. Gao GP, et al. Among authors: johnston j. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11854-9. doi: 10.1073/pnas.182412299. Epub 2002 Aug 21. Proc Natl Acad Sci U S A. 2002. PMID: 12192090 Free PMC article.
Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model.
Johnston J, Tazelaar J, Rivera VM, Clackson T, Gao GP, Wilson JM. Johnston J, et al. Mol Ther. 2003 Apr;7(4):493-7. doi: 10.1016/s1525-0016(03)00043-1. Mol Ther. 2003. PMID: 12727112
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