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Acetylcysteine has No Mechanistic Effect in Patients at Risk of Contrast-Induced Nephropathy: A Failure of Academic Clinical Science.
Sandilands EA, Rees JMB, Raja K, Dhaun N, Morrison EE, Hickson K, Wraight J, Gray T, Briody L, Cameron S, Thompson AP, Johnston NR, Uren N, Goddard J, Treweeke A, Rushworth G, Webb DJ, Bateman DN, Norrie J, Megson IL, Eddleston M. Sandilands EA, et al. Among authors: johnston nr. Clin Pharmacol Ther. 2022 Jun;111(6):1222-1238. doi: 10.1002/cpt.2541. Epub 2022 Feb 23. Clin Pharmacol Ther. 2022. PMID: 35098531 Clinical Trial.
The clinical landscape for AAV gene therapies.
Kuzmin DA, Shutova MV, Johnston NR, Smith OP, Fedorin VV, Kukushkin YS, van der Loo JCM, Johnstone EC. Kuzmin DA, et al. Among authors: johnston nr. Nat Rev Drug Discov. 2021 Mar;20(3):173-174. doi: 10.1038/d41573-021-00017-7. Nat Rev Drug Discov. 2021. PMID: 33495615 No abstract available.
Remote control of glucose homeostasis in vivo using photopharmacology.
Mehta ZB, Johnston NR, Nguyen-Tu MS, Broichhagen J, Schultz P, Larner DP, Leclerc I, Trauner D, Rutter GA, Hodson DJ. Mehta ZB, et al. Among authors: johnston nr. Sci Rep. 2017 Mar 22;7(1):291. doi: 10.1038/s41598-017-00397-0. Sci Rep. 2017. PMID: 28331198 Free PMC article.
Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose.
Johnston NR, Mitchell RK, Haythorne E, Pessoa MP, Semplici F, Ferrer J, Piemonti L, Marchetti P, Bugliani M, Bosco D, Berishvili E, Duncanson P, Watkinson M, Broichhagen J, Trauner D, Rutter GA, Hodson DJ. Johnston NR, et al. Cell Metab. 2016 Sep 13;24(3):389-401. doi: 10.1016/j.cmet.2016.06.020. Epub 2016 Jul 21. Cell Metab. 2016. PMID: 27452146 Free PMC article.
Allosteric Optical Control of a Class B G-Protein-Coupled Receptor.
Broichhagen J, Johnston NR, von Ohlen Y, Meyer-Berg H, Jones BJ, Bloom SR, Rutter GA, Trauner D, Hodson DJ. Broichhagen J, et al. Among authors: johnston nr. Angew Chem Int Ed Engl. 2016 May 4;55(19):5865-8. doi: 10.1002/anie.201600957. Epub 2016 Apr 5. Angew Chem Int Ed Engl. 2016. PMID: 27059784 Free PMC article.
Optical Control of Insulin Secretion Using an Incretin Switch.
Broichhagen J, Podewin T, Meyer-Berg H, von Ohlen Y, Johnston NR, Jones BJ, Bloom SR, Rutter GA, Hoffmann-Röder A, Hodson DJ, Trauner D. Broichhagen J, et al. Among authors: johnston nr. Angew Chem Int Ed Engl. 2015 Dec 14;54(51):15565-9. doi: 10.1002/anie.201506384. Epub 2015 Nov 2. Angew Chem Int Ed Engl. 2015. PMID: 26585495 Free PMC article.
52 results