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The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease.
Bhattacharjee A, Reuter S, Trojnár E, Kolodziejczyk R, Seeberger H, Hyvärinen S, Uzonyi B, Szilágyi Á, Prohászka Z, Goldman A, Józsi M, Jokiranta TS. Bhattacharjee A, et al. Among authors: jokiranta ts. J Biol Chem. 2015 Apr 10;290(15):9500-10. doi: 10.1074/jbc.M114.630871. Epub 2015 Feb 6. J Biol Chem. 2015. PMID: 25659429 Free PMC article.
Complement Factor H Binds to Human Serum Apolipoprotein E and Mediates Complement Regulation on High Density Lipoprotein Particles.
Haapasalo K, van Kessel K, Nissilä E, Metso J, Johansson T, Miettinen S, Varjosalo M, Kirveskari J, Kuusela P, Chroni A, Jauhiainen M, van Strijp J, Jokiranta TS. Haapasalo K, et al. Among authors: jokiranta ts. J Biol Chem. 2015 Nov 27;290(48):28977-87. doi: 10.1074/jbc.M115.669226. Epub 2015 Oct 14. J Biol Chem. 2015. PMID: 26468283 Free PMC article.
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