Jonas JC - Search Results

1

Mechanisms of β-cell dedifferentiation in diabetes: recent findings and future research directions.

Bensellam M, Jonas JC, Laybutt DR. Bensellam M, et al. Among authors: jonas jc. J Endocrinol. 2018 Feb;236(2):R109-R143. doi: 10.1530/JOE-17-0516. Epub 2017 Dec 4. J Endocrinol. 2018. PMID: 29203573 Review.

2

Increased expression of antioxidant and antiapoptotic genes in islets that may contribute to beta-cell survival during chronic hyperglycemia.

Laybutt DR, Kaneto H, Hasenkamp W, Grey S, Jonas JC, Sgroi DC, Groff A, Ferran C, Bonner-Weir S, Sharma A, Weir GC. Laybutt DR, et al. Among authors: jonas jc. Diabetes. 2002 Feb;51(2):413-23. doi: 10.2337/diabetes.51.2.413. Diabetes. 2002. PMID: 11812749

3

Glucose-induced O₂ consumption activates hypoxia inducible factors 1 and 2 in rat insulin-secreting pancreatic beta-cells.

Bensellam M, Duvillié B, Rybachuk G, Laybutt DR, Magnan C, Guiot Y, Pouysségur J, Jonas JC. Bensellam M, et al. Among authors: jonas jc. PLoS One. 2012;7(1):e29807. doi: 10.1371/journal.pone.0029807. Epub 2012 Jan 3. PLoS One. 2012. PMID: 22235342 Free PMC article.

4

The molecular mechanisms of pancreatic β-cell glucotoxicity: recent findings and future research directions.

Bensellam M, Laybutt DR, Jonas JC. Bensellam M, et al. Among authors: jonas jc. Mol Cell Endocrinol. 2012 Nov 25;364(1-2):1-27. doi: 10.1016/j.mce.2012.08.003. Epub 2012 Aug 10. Mol Cell Endocrinol. 2012. PMID: 22885162 Review.

5

Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia.

Igoillo-Esteve M, Gurgul-Convey E, Hu A, Romagueira Bichara Dos Santos L, Abdulkarim B, Chintawar S, Marselli L, Marchetti P, Jonas JC, Eizirik DL, Pandolfo M, Cnop M. Igoillo-Esteve M, et al. Among authors: jonas jc. Hum Mol Genet. 2015 Apr 15;24(8):2274-86. doi: 10.1093/hmg/ddu745. Epub 2014 Dec 30. Hum Mol Genet. 2015. PMID: 25552656

6

Hypoxia reduces ER-to-Golgi protein trafficking and increases cell death by inhibiting the adaptive unfolded protein response in mouse beta cells.

Bensellam M, Maxwell EL, Chan JY, Luzuriaga J, West PK, Jonas JC, Gunton JE, Laybutt DR. Bensellam M, et al. Among authors: jonas jc. Diabetologia. 2016 Jul;59(7):1492-1502. doi: 10.1007/s00125-016-3947-y. Epub 2016 Apr 4. Diabetologia. 2016. PMID: 27039902

7

NADPH oxidase-2 does not contribute to β-cell glucotoxicity in cultured pancreatic islets from C57BL/6J mice.

de Souza AH, Santos LRB, Roma LP, Bensellam M, Carpinelli AR, Jonas JC. de Souza AH, et al. Among authors: jonas jc. Mol Cell Endocrinol. 2017 Jan 5;439:354-362. doi: 10.1016/j.mce.2016.09.022. Epub 2016 Sep 22. Mol Cell Endocrinol. 2017. PMID: 27664519

8

Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.

Cosentino C, Toivonen S, Diaz Villamil E, Atta M, Ravanat JL, Demine S, Schiavo AA, Pachera N, Deglasse JP, Jonas JC, Balboa D, Otonkoski T, Pearson ER, Marchetti P, Eizirik DL, Cnop M, Igoillo-Esteve M. Cosentino C, et al. Among authors: jonas jc. Nucleic Acids Res. 2018 Nov 2;46(19):10302-10318. doi: 10.1093/nar/gky839. Nucleic Acids Res. 2018. PMID: 30247717 Free PMC article.

9

Phlda3 regulates beta cell survival during stress.

Bensellam M, Chan JY, Lee K, Joglekar MV, Hardikar AA, Loudovaris T, Thomas HE, Jonas JC, Laybutt DR. Bensellam M, et al. Among authors: jonas jc. Sci Rep. 2019 Sep 6;9(1):12827. doi: 10.1038/s41598-019-49289-5. Sci Rep. 2019. PMID: 31492921 Free PMC article.

10

Metallothionein 1 negatively regulates glucose-stimulated insulin secretion and is differentially expressed in conditions of beta cell compensation and failure in mice and humans.

Bensellam M, Shi YC, Chan JY, Laybutt DR, Chae H, Abou-Samra M, Pappas EG, Thomas HE, Gilon P, Jonas JC. Bensellam M, et al. Among authors: jonas jc. Diabetologia. 2019 Dec;62(12):2273-2286. doi: 10.1007/s00125-019-05008-3. Epub 2019 Oct 17. Diabetologia. 2019. PMID: 31624901

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