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Pancreatic β-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
Cosentino C, Toivonen S, Diaz Villamil E, Atta M, Ravanat JL, Demine S, Schiavo AA, Pachera N, Deglasse JP, Jonas JC, Balboa D, Otonkoski T, Pearson ER, Marchetti P, Eizirik DL, Cnop M, Igoillo-Esteve M. Cosentino C, et al. Among authors: jonas jc. Nucleic Acids Res. 2018 Nov 2;46(19):10302-10318. doi: 10.1093/nar/gky839. Nucleic Acids Res. 2018. PMID: 30247717 Free PMC article.
Unveiling a common mechanism of apoptosis in β-cells and neurons in Friedreich's ataxia.
Igoillo-Esteve M, Gurgul-Convey E, Hu A, Romagueira Bichara Dos Santos L, Abdulkarim B, Chintawar S, Marselli L, Marchetti P, Jonas JC, Eizirik DL, Pandolfo M, Cnop M. Igoillo-Esteve M, et al. Among authors: jonas jc. Hum Mol Genet. 2015 Apr 15;24(8):2274-86. doi: 10.1093/hmg/ddu745. Epub 2014 Dec 30. Hum Mol Genet. 2015. PMID: 25552656
Exenatide induces frataxin expression and improves mitochondrial function in Friedreich ataxia.
Igoillo-Esteve M, Oliveira AF, Cosentino C, Fantuzzi F, Demarez C, Toivonen S, Hu A, Chintawar S, Lopes M, Pachera N, Cai Y, Abdulkarim B, Rai M, Marselli L, Marchetti P, Tariq M, Jonas JC, Boscolo M, Pandolfo M, Eizirik DL, Cnop M. Igoillo-Esteve M, et al. Among authors: jonas jc. JCI Insight. 2020 Jan 30;5(2):e134221. doi: 10.1172/jci.insight.134221. JCI Insight. 2020. PMID: 31877117 Free PMC article.
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide.
Montiel V, Bella R, Michel LYM, Esfahani H, De Mulder D, Robinson EL, Deglasse JP, Tiburcy M, Chow PH, Jonas JC, Gilon P, Steinhorn B, Michel T, Beauloye C, Bertrand L, Farah C, Dei Zotti F, Debaix H, Bouzin C, Brusa D, Horman S, Vanoverschelde JL, Bergmann O, Gilis D, Rooman M, Ghigo A, Geninatti-Crich S, Yool A, Zimmermann WH, Roderick HL, Devuyst O, Balligand JL. Montiel V, et al. Among authors: jonas jc. Sci Transl Med. 2020 Oct 7;12(564):eaay2176. doi: 10.1126/scitranslmed.aay2176. Sci Transl Med. 2020. PMID: 33028705
In depth functional characterization of human induced pluripotent stem cell-derived beta cells in vitro and in vivo.
Fantuzzi F, Toivonen S, Schiavo AA, Chae H, Tariq M, Sawatani T, Pachera N, Cai Y, Vinci C, Virgilio E, Ladriere L, Suleiman M, Marchetti P, Jonas JC, Gilon P, Eizirik DL, Igoillo-Esteve M, Cnop M. Fantuzzi F, et al. Among authors: jonas jc. Front Cell Dev Biol. 2022 Aug 17;10:967765. doi: 10.3389/fcell.2022.967765. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36060810 Free PMC article.
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