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Virtual Screening Approaches to Identify Promising Multitarget-Directed Ligands for the Treatment of Autism Spectrum Disorder.
Molecules. 2024 Nov 7;29(22):5271. doi: 10.3390/molecules29225271.
Molecules. 2024.
PMID: 39598660
Free PMC article.
The virtual screening protocol integrated predictions from SwissTargetPrediction, SEA, and PPB2 tools, along with molecular docking simulations conducted using GOLD 5.3 and Glide 7.5 software. Among the selected ligands, compounds 25 and 30 blocked radioligand binding to t …
The virtual screening protocol integrated predictions from SwissTargetPrediction, SEA, and PPB2 tools, along with molecular docking simulati …
Dual Action of Dipyridothiazine and Quinobenzothiazine Derivatives-Anticancer and Cholinesterase-Inhibiting Activity.
Jończyk J, Godyń J, Stawarska E, Morak-Młodawska B, Jeleń M, Pluta K, Malawska B.
Jończyk J, et al.
Molecules. 2020 Jun 3;25(11):2604. doi: 10.3390/molecules25112604.
Molecules. 2020.
PMID: 32503288
Free PMC article.
The virtual screening of a library of 120 ligands, which are the derivatives of azaphenothiazine, led to the identification of 25 compounds that can act as potential inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE). ...
The virtual screening of a library of 120 ligands, which are the derivatives of azaphenothiazine, led to the identification of 25 com …
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