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The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.
Franklin BS, Bossaller L, De Nardo D, Ratter JM, Stutz A, Engels G, Brenker C, Nordhoff M, Mirandola SR, Al-Amoudi A, Mangan MS, Zimmer S, Monks BG, Fricke M, Schmidt RE, Espevik T, Jones B, Jarnicki AG, Hansbro PM, Busto P, Marshak-Rothstein A, Hornemann S, Aguzzi A, Kastenmüller W, Latz E. Franklin BS, et al. Among authors: jones b. Nat Immunol. 2014 Aug;15(8):727-37. doi: 10.1038/ni.2913. Epub 2014 Jun 22. Nat Immunol. 2014. PMID: 24952505 Free PMC article.
MicroRNA-21 drives severe, steroid-insensitive experimental asthma by amplifying phosphoinositide 3-kinase-mediated suppression of histone deacetylase 2.
Kim RY, Horvat JC, Pinkerton JW, Starkey MR, Essilfie AT, Mayall JR, Nair PM, Hansbro NG, Jones B, Haw TJ, Sunkara KP, Nguyen TH, Jarnicki AG, Keely S, Mattes J, Adcock IM, Foster PS, Hansbro PM. Kim RY, et al. Among authors: jones b. J Allergy Clin Immunol. 2017 Feb;139(2):519-532. doi: 10.1016/j.jaci.2016.04.038. Epub 2016 Jun 10. J Allergy Clin Immunol. 2017. PMID: 27448447 Free article.
Chronic cigarette smoke exposure induces systemic hypoxia that drives intestinal dysfunction.
Fricker M, Goggins BJ, Mateer S, Jones B, Kim RY, Gellatly SL, Jarnicki AG, Powell N, Oliver BG, Radford-Smith G, Talley NJ, Walker MM, Keely S, Hansbro PM. Fricker M, et al. Among authors: jones b. JCI Insight. 2018 Feb 8;3(3):e94040. doi: 10.1172/jci.insight.94040. eCollection 2018 Feb 8. JCI Insight. 2018. PMID: 29415878 Free PMC article.
Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.
Liu G, Cooley MA, Jarnicki AG, Borghuis T, Nair PM, Tjin G, Hsu AC, Haw TJ, Fricker M, Harrison CL, Jones B, Hansbro NG, Wark PA, Horvat JC, Argraves WS, Oliver BG, Knight DA, Burgess JK, Hansbro PM. Liu G, et al. Among authors: jones b. JCI Insight. 2019 Jul 25;5(16):e124529. doi: 10.1172/jci.insight.124529. JCI Insight. 2019. PMID: 31343988 Free PMC article.
Time-resolved proteomic profiling of cigarette smoke-induced experimental chronic obstructive pulmonary disease.
Skerrett-Byrne DA, Bromfield EG, Murray HC, Jamaluddin MFB, Jarnicki AG, Fricker M, Essilfie AT, Jones B, Haw TJ, Hampsey D, Anderson AL, Nixon B, Scott RJ, Wark PAB, Dun MD, Hansbro PM. Skerrett-Byrne DA, et al. Among authors: jones b. Respirology. 2021 Oct;26(10):960-973. doi: 10.1111/resp.14111. Epub 2021 Jul 5. Respirology. 2021. PMID: 34224176
Necroptosis Signaling Promotes Inflammation, Airway Remodeling, and Emphysema in Chronic Obstructive Pulmonary Disease.
Lu Z, Van Eeckhoutte HP, Liu G, Nair PM, Jones B, Gillis CM, Nalkurthi BC, Verhamme F, Buyle-Huybrecht T, Vandenabeele P, Vanden Berghe T, Brusselle GG, Horvat JC, Murphy JM, Wark PA, Bracke KR, Fricker M, Hansbro PM. Lu Z, et al. Among authors: jones b. Am J Respir Crit Care Med. 2021 Sep 15;204(6):667-681. doi: 10.1164/rccm.202009-3442OC. Am J Respir Crit Care Med. 2021. PMID: 34133911
Animal models of COPD: What do they tell us?
Jones B, Donovan C, Liu G, Gomez HM, Chimankar V, Harrison CL, Wiegman CH, Adcock IM, Knight DA, Hirota JA, Hansbro PM. Jones B, et al. Respirology. 2017 Jan;22(1):21-32. doi: 10.1111/resp.12908. Epub 2016 Oct 12. Respirology. 2017. PMID: 27731525 Free article. Review.
Roles for T/B lymphocytes and ILC2s in experimental chronic obstructive pulmonary disease.
Donovan C, Starkey MR, Kim RY, Rana BMJ, Barlow JL, Jones B, Haw TJ, Mono Nair P, Budden K, Cameron GJM, Horvat JC, Wark PA, Foster PS, McKenzie ANJ, Hansbro PM. Donovan C, et al. Among authors: jones b. J Leukoc Biol. 2019 Jan;105(1):143-150. doi: 10.1002/JLB.3AB0518-178R. Epub 2018 Sep 27. J Leukoc Biol. 2019. PMID: 30260499 Free PMC article.
Chronic Obstructive Pulmonary Disease and Lung Cancer: Underlying Pathophysiology and New Therapeutic Modalities.
Eapen MS, Hansbro PM, Larsson-Callerfelt AK, Jolly MK, Myers S, Sharma P, Jones B, Rahman MA, Markos J, Chia C, Larby J, Haug G, Hardikar A, Weber HC, Mabeza G, Cavalheri V, Khor YH, McDonald CF, Sohal SS. Eapen MS, et al. Among authors: jones b. Drugs. 2018 Nov;78(16):1717-1740. doi: 10.1007/s40265-018-1001-8. Drugs. 2018. PMID: 30392114 Review.
7,092 results