Jones CD - Search Results

1

Antiestrogens. 3. Estrogen receptor affinities and antiproliferative effects in MCF-7 cells of phenolic analogues of trioxifene, [3,4-dihydro-2-(4- methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]- phenyl]methanone.

Jones CD, Blaszczak LC, Goettel ME, Suarez T, Crowell TA, Mabry TE, Ruenitz PC, Srivatsan V. Jones CD, et al. J Med Chem. 1992 Mar 6;35(5):931-8. doi: 10.1021/jm00083a019. J Med Chem. 1992. PMID: 1548683

2

Synthesis and antiestrogenic activity of [3,4-dihydro-2-(4-methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]-phenyl]methanone, methanesulfonic acid salt.

Jones CD, Suarez T, Massey EH, Black LJ, Tinsley FC. Jones CD, et al. J Med Chem. 1979 Aug;22(8):962-6. doi: 10.1021/jm00194a015. J Med Chem. 1979. PMID: 490541

3

The in vitro anti-hepatitis B virus activity of FIAU [1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl-5-iodo)uracil] is selective, reversible, and determined, at least in part, by the host cell.

Staschke KA, Colacino JM, Mabry TE, Jones CD. Staschke KA, et al. Among authors: jones cd. Antiviral Res. 1994 Jan;23(1):45-61. doi: 10.1016/0166-3542(94)90032-9. Antiviral Res. 1994. PMID: 8141592

4

Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene.

Grese TA, Cho S, Finley DR, Godfrey AG, Jones CD, Lugar CW 3rd, Martin MJ, Matsumoto K, Pennington LD, Winter MA, Adrian MD, Cole HW, Magee DE, Phillips DL, Rowley ER, Short LL, Glasebrook AL, Bryant HU. Grese TA, et al. Among authors: jones cd. J Med Chem. 1997 Jan 17;40(2):146-67. doi: 10.1021/jm9606352. J Med Chem. 1997. PMID: 9003514

5

Sensitive and specific radioimmunoassay for fialuridine: initial assessment of pharmacokinetics after single oral doses to healthy volunteers.

Bowsher RR, Compton JA, Kirkwood JA, Place GD, Jones CD, Mabry TE, Hyslop DL, Hatcher BL, DeSante KA. Bowsher RR, et al. Among authors: jones cd. Antimicrob Agents Chemother. 1994 Sep;38(9):2134-42. doi: 10.1128/AAC.38.9.2134. Antimicrob Agents Chemother. 1994. PMID: 7811032 Free PMC article.

6

Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups.

Jones CD, Winter MA, Hirsch KS, Stamm N, Taylor HM, Holden HE, Davenport JD, Krumkalns EV, Suhr RG. Jones CD, et al. J Med Chem. 1990 Jan;33(1):416-29. doi: 10.1021/jm00163a065. J Med Chem. 1990. PMID: 2296032

7

Nonsteroidal inhibitors of human type I steroid 5-alpha-reductase.

Jones CD, Audia JE, Lawhorn DE, McQuaid LA, Neubauer BL, Pike AJ, Pennington PA, Stamm NB, Toomey RE, Hirsch KS. Jones CD, et al. J Med Chem. 1993 Feb 5;36(3):421-3. doi: 10.1021/jm00055a014. J Med Chem. 1993. PMID: 8381185 No abstract available.

8

Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl] [4-[2-(1-piperidinyl)ethoxy]-phenyl]methanone hydrochloride (LY156758), a remarkably effective estrogen antagonist with only minimal intrinsic estrogenicity.

Jones CD, Jevnikar MG, Pike AJ, Peters MK, Black LJ, Thompson AR, Falcone JF, Clemens JA. Jones CD, et al. J Med Chem. 1984 Aug;27(8):1057-66. doi: 10.1021/jm00374a021. J Med Chem. 1984. PMID: 6431104

9

Synthesis and antiviral activity of prodrugs of the nucleoside 1-[2',3'-dideoxy-3'-C-(hydroxymethyl)-beta-D-erythropentofuranosyl] cytosine.

Mauldin SC, Paget CJ Jr, Jones CD, Colacino JM, Baxter AJ, Staschke KA, Johansson NG, Vrang L. Mauldin SC, et al. Among authors: jones cd. Bioorg Med Chem. 1998 May;6(5):577-85. doi: 10.1016/s0968-0896(98)00020-0. Bioorg Med Chem. 1998. PMID: 9629471

10

The selective estrogen receptor modulator trioxifene (LY133314) inhibits metastasis and extends survival in the PAIII rat prostatic carcinoma model.

Neubauer BL, McNulty AM, Chedid M, Chen K, Goode RL, Johnson MA, Jones CD, Krishnan V, Lynch R, Osborne HE, Graff JR. Neubauer BL, et al. Among authors: jones cd. Cancer Res. 2003 Sep 15;63(18):6056-62. Cancer Res. 2003. PMID: 14522935

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