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Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.
Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, Zheng H, Tanzi RE, Masters CL, Bush AI. Cherny RA, et al. Among authors: jones wd. Neuron. 2001 Jun;30(3):665-76. doi: 10.1016/s0896-6273(01)00317-8. Neuron. 2001. PMID: 11430801 Free article.
Copper mediates dityrosine cross-linking of Alzheimer's amyloid-beta.
Atwood CS, Perry G, Zeng H, Kato Y, Jones WD, Ling KQ, Huang X, Moir RD, Wang D, Sayre LM, Smith MA, Chen SG, Bush AI. Atwood CS, et al. Among authors: jones wd. Biochemistry. 2004 Jan 20;43(2):560-8. doi: 10.1021/bi0358824. Biochemistry. 2004. PMID: 14717612
Germline homozygous missense DEPDC5 variants cause severe refractory early-onset epilepsy, macrocephaly and bilateral polymicrogyria.
Ververi A, Zagaglia S, Menzies L, Baptista J, Caswell R, Baulac S, Ellard S, Lynch S, Consortium GER, Jacques TS, Chawla MS, Heier M, Kulseth MA, Mero IL, Våtevik AK, Kraoua I, Rhouma HB, Younes TB, Miladi Z, Turki IBY, Jones WD, Clement E, Eltze C, Mankad K, Merve A, Parker J, Hoskins B, Pressler R, Sudhakar S, DeVile C, Homfray T, Kaliakatsos M, Ponnudas PP, Robinson R, Keim SMB, Habibi I, Reymond A, Sisodiya SM, Hurst JA. Ververi A, et al. Among authors: jones wd. Hum Mol Genet. 2022 Sep 6:ddac225. doi: 10.1093/hmg/ddac225. Online ahead of print. Hum Mol Genet. 2022. PMID: 36067010
Advancing NGS quality control to enable measurement of actionable mutations in circulating tumor DNA.
Willey JC, Morrison TB, Austermiller B, Crawford EL, Craig DJ, Blomquist TM, Jones WD, Wali A, Lococo JS, Haseley N, Richmond TA, Novoradovskaya N, Kusko R, Chen G, Li QZ, Johann DJ Jr, Deveson IW, Mercer TR, Wu L, Xu J. Willey JC, et al. Among authors: jones wd. Cell Rep Methods. 2021 Nov 3;1(7):100106. doi: 10.1016/j.crmeth.2021.100106. eCollection 2021 Nov 22. Cell Rep Methods. 2021. PMID: 35475002 Free PMC article.
207 results