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Page 1
Regulatory T cells: mechanisms of differentiation and function.
Josefowicz SZ, Lu LF, Rudensky AY. Josefowicz SZ, et al. Annu Rev Immunol. 2012;30:531-64. doi: 10.1146/annurev.immunol.25.022106.141623. Epub 2012 Jan 6. Annu Rev Immunol. 2012. PMID: 22224781 Free PMC article. Review.
Epigenetic memory of coronavirus infection in innate immune cells and their progenitors.
Cheong JG, Ravishankar A, Sharma S, Parkhurst CN, Grassmann SA, Wingert CK, Laurent P, Ma S, Paddock L, Miranda IC, Karakaslar EO, Nehar-Belaid D, Thibodeau A, Bale MJ, Kartha VK, Yee JK, Mays MY, Jiang C, Daman AW, Martinez de Paz A, Ahimovic D, Ramos V, Lercher A, Nielsen E, Alvarez-Mulett S, Zheng L, Earl A, Yallowitz A, Robbins L, LaFond E, Weidman KL, Racine-Brzostek S, Yang HS, Price DR, Leyre L, Rendeiro AF, Ravichandran H, Kim J, Borczuk AC, Rice CM, Jones RB, Schenck EJ, Kaner RJ, Chadburn A, Zhao Z, Pascual V, Elemento O, Schwartz RE, Buenrostro JD, Niec RE, Barrat FJ, Lief L, Sun JC, Ucar D, Josefowicz SZ. Cheong JG, et al. Among authors: josefowicz sz. Cell. 2023 Aug 31;186(18):3882-3902.e24. doi: 10.1016/j.cell.2023.07.019. Epub 2023 Aug 18. Cell. 2023. PMID: 37597510 Free PMC article.
Histone H3.3 phosphorylation amplifies stimulation-induced transcription.
Armache A, Yang S, Martínez de Paz A, Robbins LE, Durmaz C, Cheong JQ, Ravishankar A, Daman AW, Ahimovic DJ, Klevorn T, Yue Y, Arslan T, Lin S, Panchenko T, Hrit J, Wang M, Thudium S, Garcia BA, Korb E, Armache KJ, Rothbart SB, Hake SB, Allis CD, Li H, Josefowicz SZ. Armache A, et al. Among authors: josefowicz sz. Nature. 2020 Jul;583(7818):852-857. doi: 10.1038/s41586-020-2533-0. Epub 2020 Jul 22. Nature. 2020. PMID: 32699416 Free PMC article.
Innate immunity-With an adaptive twist.
Josefowicz SZ, Sun JC. Josefowicz SZ, et al. Immunol Rev. 2024 May;323(1):5-7. doi: 10.1111/imr.13334. Epub 2024 Apr 17. Immunol Rev. 2024. PMID: 38628138 No abstract available.
Fungal microbiota sustains lasting immune activation of neutrophils and their progenitors in severe COVID-19.
Kusakabe T, Lin WY, Cheong JG, Singh G, Ravishankar A, Yeung ST, Mesko M, DeCelie MB, Carriche G, Zhao Z, Rand S, Doron I, Putzel GG, Worgall S, Cushing M, Westblade L, Inghirami G, Parkhurst CN, Guo CJ, Schotsaert M, García-Sastre A, Josefowicz SZ, Salvatore M, Iliev ID. Kusakabe T, et al. Among authors: josefowicz sz. Nat Immunol. 2023 Nov;24(11):1879-1889. doi: 10.1038/s41590-023-01637-4. Epub 2023 Oct 23. Nat Immunol. 2023. PMID: 37872315 Free PMC article.
Broad-spectrum antibiotics disrupt homeostatic efferocytosis.
Saavedra PHV, Trzeciak AJ, Lipshutz A, Daman AW, O'Neal AJ, Liu ZL, Wang Z, Romero-Pichardo JE, Rojas WS, Zago G, van den Brink MRM, Josefowicz SZ, Lucas CD, Anderson CJ, Rudensky AY, Perry JSA. Saavedra PHV, et al. Among authors: josefowicz sz. Nat Metab. 2024 Sep;6(9):1682-1694. doi: 10.1038/s42255-024-01107-7. Epub 2024 Aug 9. Nat Metab. 2024. PMID: 39122784 Free PMC article.
Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumors.
Hegde S, Giotti B, Soong BY, Halasz L, Berichel JL, Magen A, Kloeckner B, Mattiuz R, Park MD, Marks A, Belabed M, Hamon P, Chin T, Troncoso L, Lee JJ, Ahimovic D, Bale M, Chung G, D'souza D, Angeliadis K, Dawson T, Kim-Schulze S, Flores RM, Kaufman AJ, Ginhoux F, Josefowicz SZ, Ma S, Tsankov AM, Marron TU, Brown BD, Merad M. Hegde S, et al. Among authors: josefowicz sz. bioRxiv [Preprint]. 2024 Jun 28:2024.06.24.600383. doi: 10.1101/2024.06.24.600383. bioRxiv. 2024. PMID: 38979166 Free PMC article. Preprint.
Transcriptional Activation of Regenerative Hematopoiesis via Vascular Niche Sensing.
Itkin T, Houghton S, Schreiner R, Lin Y, Badwe CR, Voisin V, Murison A, Seyedhassantehrani N, Kaufmann KB, Garcia-Prat L, Booth GT, Geng F, Liu Y, Gomez-Salinero JM, Shieh JH, Redmond D, Xiang JZ, Josefowicz SZ, Trapnell C, Spencer JA, Zangi L, Hadland B, Dick JE, Xie SZ, Rafii S. Itkin T, et al. Among authors: josefowicz sz. bioRxiv [Preprint]. 2023 Mar 29:2023.03.27.534417. doi: 10.1101/2023.03.27.534417. bioRxiv. 2023. PMID: 37034724 Free PMC article. Preprint.
Antiviral innate immune memory in alveolar macrophages following SARS-CoV-2 infection.
Lercher A, Cheong JG, Jiang C, Hoffmann HH, Ashbrook AW, Yin YS, Quirk C, DeGrace EJ, Chiriboga L, Rosenberg BR, Josefowicz SZ, Rice CM. Lercher A, et al. Among authors: josefowicz sz. bioRxiv [Preprint]. 2023 Nov 27:2023.11.24.568354. doi: 10.1101/2023.11.24.568354. bioRxiv. 2023. Update in: Immunity. 2024 Nov 12;57(11):2530-2546.e13. doi: 10.1016/j.immuni.2024.08.018. PMID: 38076887 Free PMC article. Updated. Preprint.
Circulating hematopoietic stem/progenitor cell subsets contribute to human hematopoietic homeostasis.
Quaranta P, Basso-Ricci L, Jofra Hernandez R, Pacini G, Naldini MM, Barcella M, Seffin L, Pais G, Spinozzi G, Benedicenti F, Pietrasanta C, Cheong JG, Ronchi A, Pugni L, Dionisio F, Monti I, Giannelli S, Darin S, Fraschetta F, Barera G, Ferrua F, Calbi V, Ometti M, Di Micco R, Mosca F, Josefowicz SZ, Montini E, Calabria A, Bernardo ME, Cicalese MP, Gentner B, Merelli I, Aiuti A, Scala S. Quaranta P, et al. Among authors: josefowicz sz. Blood. 2024 May 9;143(19):1937-1952. doi: 10.1182/blood.2023022666. Blood. 2024. PMID: 38446574 Free PMC article. Clinical Trial.
36 results