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Desialylation accelerates platelet clearance after refrigeration and initiates GPIbα metalloproteinase-mediated cleavage in mice.
Jansen AJ, Josefsson EC, Rumjantseva V, Liu QP, Falet H, Bergmeier W, Cifuni SM, Sackstein R, von Andrian UH, Wagner DD, Hartwig JH, Hoffmeister KM. Jansen AJ, et al. Among authors: josefsson ec. Blood. 2012 Feb 2;119(5):1263-73. doi: 10.1182/blood-2011-05-355628. Epub 2011 Nov 18. Blood. 2012. PMID: 22101895 Free PMC article.
Dual roles for hepatic lectin receptors in the clearance of chilled platelets.
Rumjantseva V, Grewal PK, Wandall HH, Josefsson EC, Sørensen AL, Larson G, Marth JD, Hartwig JH, Hoffmeister KM. Rumjantseva V, et al. Among authors: josefsson ec. Nat Med. 2009 Nov;15(11):1273-80. doi: 10.1038/nm.2030. Epub 2009 Sep 27. Nat Med. 2009. PMID: 19783995 Free PMC article.
Glycosylation restores survival of chilled blood platelets.
Hoffmeister KM, Josefsson EC, Isaac NA, Clausen H, Hartwig JH, Stossel TP. Hoffmeister KM, et al. Among authors: josefsson ec. Science. 2003 Sep 12;301(5639):1531-4. doi: 10.1126/science.1085322. Science. 2003. PMID: 12970565
The origin and function of platelet glycosyltransferases.
Wandall HH, Rumjantseva V, Sørensen AL, Patel-Hett S, Josefsson EC, Bennett EP, Italiano JE Jr, Clausen H, Hartwig JH, Hoffmeister KM. Wandall HH, et al. Among authors: josefsson ec. Blood. 2012 Jul 19;120(3):626-35. doi: 10.1182/blood-2012-02-409235. Epub 2012 May 21. Blood. 2012. PMID: 22613794 Free PMC article.
Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan.
Liu ZJ, Hoffmeister KM, Hu Z, Mager DE, Ait-Oudhia S, Debrincat MA, Pleines I, Josefsson EC, Kile BT, Italiano J Jr, Ramsey H, Grozovsky R, Veng-Pedersen P, Chavda C, Sola-Visner M. Liu ZJ, et al. Among authors: josefsson ec. Blood. 2014 May 29;123(22):3381-9. doi: 10.1182/blood-2013-06-508200. Epub 2014 Mar 5. Blood. 2014. PMID: 24599546 Free PMC article.
Bcl-xL-inhibitory BH3 mimetics can induce a transient thrombocytopathy that undermines the hemostatic function of platelets.
Schoenwaelder SM, Jarman KE, Gardiner EE, Hua M, Qiao J, White MJ, Josefsson EC, Alwis I, Ono A, Willcox A, Andrews RK, Mason KD, Salem HH, Huang DC, Kile BT, Roberts AW, Jackson SP. Schoenwaelder SM, et al. Among authors: josefsson ec. Blood. 2011 Aug 11;118(6):1663-74. doi: 10.1182/blood-2011-04-347849. Epub 2011 Jun 14. Blood. 2011. PMID: 21673344 Free article.
The RNA-binding protein SRSF3 has an essential role in megakaryocyte maturation and platelet production.
Heazlewood SY, Ahmad T, Mohenska M, Guo BB, Gangatirkar P, Josefsson EC, Ellis SL, Ratnadiwakara M, Cao H, Cao B, Heazlewood CK, Williams B, Fulton M, White JF, Ramialison M, Nilsson SK, Änkö ML. Heazlewood SY, et al. Among authors: josefsson ec. Blood. 2022 Mar 3;139(9):1359-1373. doi: 10.1182/blood.2021013826. Blood. 2022. PMID: 34852174 Free PMC article.
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