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The role of motility as a virulence factor in bacteria.
Josenhans C, Suerbaum S. Josenhans C, et al. Int J Med Microbiol. 2002 Mar;291(8):605-14. doi: 10.1078/1438-4221-00173. Int J Med Microbiol. 2002. PMID: 12008914 Review.
Comparative ultrastructural and functional studies of Helicobacter pylori and Helicobacter mustelae flagellin mutants: both flagellin subunits, FlaA and FlaB, are necessary for full motility in Helicobacter species.
Josenhans C, Labigne A, Suerbaum S. Josenhans C, et al. J Bacteriol. 1995 Jun;177(11):3010-20. doi: 10.1128/jb.177.11.3010-3020.1995. J Bacteriol. 1995. PMID: 7768796 Free PMC article.
Virulence factors of Helicobacter pylori: implications for vaccine development.
Suerbaum S, Josenhans C. Suerbaum S, et al. Among authors: josenhans c. Mol Med Today. 1999 Jan;5(1):32-9. doi: 10.1016/s1357-4310(98)01390-2. Mol Med Today. 1999. PMID: 10088130 Review.
Switching of flagellar motility in Helicobacter pylori by reversible length variation of a short homopolymeric sequence repeat in fliP, a gene encoding a basal body protein.
Josenhans C, Eaton KA, Thevenot T, Suerbaum S. Josenhans C, et al. Infect Immun. 2000 Aug;68(8):4598-603. doi: 10.1128/iai.68.8.4598-4603.2000. Infect Immun. 2000. PMID: 10899861 Free PMC article.
All of these motile strains had a C(8) repeat and consequently a contiguous fliP reading frame. By screening approximately 50,000 colonies of 26695(C9) for motility in soft agar, a motile revertant with a C(8) repeat could be isolated, proving that the described swi …
All of these motile strains had a C(8) repeat and consequently a contiguous fliP reading frame. By screening approximately 50,000 col …
Functional characterization of the antagonistic flagellar late regulators FliA and FlgM of Helicobacter pylori and their effects on the H. pylori transcriptome.
Josenhans C, Niehus E, Amersbach S, Hörster A, Betz C, Drescher B, Hughes KT, Suerbaum S. Josenhans C, et al. Mol Microbiol. 2002 Jan;43(2):307-22. doi: 10.1046/j.1365-2958.2002.02765.x. Mol Microbiol. 2002. PMID: 11985711
The neuA/flmD gene cluster of Helicobacter pylori is involved in flagellar biosynthesis and flagellin glycosylation.
Josenhans C, Vossebein L, Friedrich S, Suerbaum S. Josenhans C, et al. FEMS Microbiol Lett. 2002 May 7;210(2):165-72. doi: 10.1111/j.1574-6968.2002.tb11176.x. FEMS Microbiol Lett. 2002. PMID: 12044670
Bacterial genomics: seven years on.
Suerbaum S, Josenhans C, Claus H, Frosch M. Suerbaum S, et al. Among authors: josenhans c. Trends Microbiol. 2002 Aug;10(8):351-3. doi: 10.1016/s0966-842x(02)02398-3. Trends Microbiol. 2002. PMID: 12160624 No abstract available.
Growth phase-dependent and differential transcriptional control of flagellar genes in Helicobacter pylori.
Niehus E, Ye F, Suerbaum S, Josenhans C. Niehus E, et al. Among authors: josenhans c. Microbiology (Reading). 2002 Dec;148(Pt 12):3827-3837. doi: 10.1099/00221287-148-12-3827. Microbiology (Reading). 2002. PMID: 12480886
The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus.
Suerbaum S, Josenhans C, Sterzenbach T, Drescher B, Brandt P, Bell M, Droge M, Fartmann B, Fischer HP, Ge Z, Horster A, Holland R, Klein K, Konig J, Macko L, Mendz GL, Nyakatura G, Schauer DB, Shen Z, Weber J, Frosch M, Fox JG. Suerbaum S, et al. Among authors: josenhans c. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7901-6. doi: 10.1073/pnas.1332093100. Epub 2003 Jun 16. Proc Natl Acad Sci U S A. 2003. PMID: 12810954 Free PMC article.
H. hepaticus lacks orthologs of most known H. pylori virulence factors, including adhesins, the VacA cytotoxin, and almost all cag pathogenicity island proteins, but has orthologs of the C. jejuni adhesin PEB1 and the cytolethal distending toxin (CDT). The genome contains …
H. hepaticus lacks orthologs of most known H. pylori virulence factors, including adhesins, the VacA cytotoxin, and almost all cag pathogeni …
Helicobacter pylori flagellins have very low intrinsic activity to stimulate human gastric epithelial cells via TLR5.
Lee SK, Stack A, Katzowitsch E, Aizawa SI, Suerbaum S, Josenhans C. Lee SK, et al. Among authors: josenhans c. Microbes Infect. 2003 Dec;5(15):1345-56. doi: 10.1016/j.micinf.2003.09.018. Microbes Infect. 2003. PMID: 14670447
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