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127 results
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Gamma-tubulin is a centrosomal protein required for cell cycle-dependent microtubule nucleation.
Joshi HC, Palacios MJ, McNamara L, Cleveland DW. Joshi HC, et al. Nature. 1992 Mar 5;356(6364):80-3. doi: 10.1038/356080a0. Nature. 1992. PMID: 1538786
In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).
Naik PK, Lopus M, Aneja R, Vangapandu SN, Joshi HC. Naik PK, et al. Among authors: joshi hc. J Comput Aided Mol Des. 2012 Feb;26(2):233-47. doi: 10.1007/s10822-011-9508-z. Epub 2011 Dec 15. J Comput Aided Mol Des. 2012. PMID: 22170255
Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis.
Ye K, Zhou J, Landen JW, Bradbury EM, Joshi HC. Ye K, et al. Among authors: joshi hc. J Biol Chem. 2001 Dec 14;276(50):46697-700. doi: 10.1074/jbc.C100550200. Epub 2001 Oct 25. J Biol Chem. 2001. PMID: 11679575
Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responses.
Ke Y, Ye K, Grossniklaus HE, Archer DR, Joshi HC, Kapp JA. Ke Y, et al. Among authors: joshi hc. Cancer Immunol Immunother. 2000 Jul;49(4-5):217-25. doi: 10.1007/s002620000109. Cancer Immunol Immunother. 2000. PMID: 10941904
Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cells.
Ye K, Ke Y, Keshava N, Shanks J, Kapp JA, Tekmal RR, Petros J, Joshi HC. Ye K, et al. Among authors: joshi hc. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1601-6. doi: 10.1073/pnas.95.4.1601. Proc Natl Acad Sci U S A. 1998. PMID: 9465062 Free PMC article.
A novel cell-cycle-dependent 350-kDa nuclear protein: C-terminal domain sufficient for nuclear localization.
Li Q, Ke Y, Kapp JA, Fertig N, Medsger TA Jr, Joshi HC. Li Q, et al. Among authors: joshi hc. Biochem Biophys Res Commun. 1995 Jul 6;212(1):220-8. doi: 10.1006/bbrc.1995.1959. Biochem Biophys Res Commun. 1995. PMID: 7612011
Gamma-tubulin reorganization during mouse fertilization and early development.
Palacios MJ, Joshi HC, Simerly C, Schatten G. Palacios MJ, et al. Among authors: joshi hc. J Cell Sci. 1993 Feb;104 ( Pt 2):383-9. J Cell Sci. 1993. PMID: 8505367
Noscapine and analogues as potential chemotherapeutic agents.
Joshi HC, Zhou J. Joshi HC, et al. Drug News Perspect. 2000 Nov;13(9):543-6. doi: 10.1358/dnp.2000.13.9.858482. Drug News Perspect. 2000. PMID: 12879125
gamma-Tubulin and microtubule organization in plants.
Joshi HC, Palevitz BA. Joshi HC, et al. Trends Cell Biol. 1996 Feb;6(2):41-4. doi: 10.1016/0962-8924(96)81008-7. Trends Cell Biol. 1996. PMID: 15157488
Centrosome reduction during mouse spermiogenesis.
Manandhar G, Sutovsky P, Joshi HC, Stearns T, Schatten G. Manandhar G, et al. Among authors: joshi hc. Dev Biol. 1998 Nov 15;203(2):424-34. doi: 10.1006/dbio.1998.8947. Dev Biol. 1998. PMID: 9808791
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