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Activated stat-3 in melanoma.
Messina JL, Yu H, Riker AI, Munster PN, Jove RL, Daud AI. Messina JL, et al. Cancer Control. 2008 Jul;15(3):196-201. doi: 10.1177/107327480801500302. Cancer Control. 2008. PMID: 18596671
Targeting JAK1/STAT3 signaling suppresses tumor progression and metastasis in a peritoneal model of human ovarian cancer.
Wen W, Liang W, Wu J, Kowolik CM, Buettner R, Scuto A, Hsieh MY, Hong H, Brown CE, Forman SJ, Horne D, Morgan R, Wakabayashi M, Dellinger TH, Han ES, Yim JH, Jove R. Wen W, et al. Among authors: jove r. Mol Cancer Ther. 2014 Dec;13(12):3037-48. doi: 10.1158/1535-7163.MCT-14-0077. Epub 2014 Oct 15. Mol Cancer Ther. 2014. PMID: 25319391 Free PMC article.
Cotreatment with suberanoylanilide hydroxamic acid and 17-allylamino 17-demethoxygeldanamycin synergistically induces apoptosis in Bcr-Abl+ Cells sensitive and resistant to STI571 (imatinib mesylate) in association with down-regulation of Bcr-Abl, abrogation of signal transducer and activator of transcription 5 activity, and Bax conformational change.
Rahmani M, Reese E, Dai Y, Bauer C, Kramer LB, Huang M, Jove R, Dent P, Grant S. Rahmani M, et al. Among authors: jove r. Mol Pharmacol. 2005 Apr;67(4):1166-76. doi: 10.1124/mol.104.007831. Epub 2004 Dec 29. Mol Pharmacol. 2005. PMID: 15625278
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