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Molecular models of the interface between anterior pharynx-defective protein 1 (APH-1) and presenilin involving GxxxG motifs.
Jozwiak K, Krzysko KA, Bojarski L, Gacia M, Filipek S. Jozwiak K, et al. ChemMedChem. 2008 Apr;3(4):627-34. doi: 10.1002/cmdc.200700189. ChemMedChem. 2008. PMID: 18061918
Early-onset Alzheimer's disease with a de novo mutation in the presenilin 1 gene.
Golan MP, Styczyńska M, Jóźwiak K, Walecki J, Maruszak A, Pniewski J, Lugiewicz R, Filipek S, Zekanowski C, Barcikowska M. Golan MP, et al. Among authors: jozwiak k. Exp Neurol. 2007 Dec;208(2):264-8. doi: 10.1016/j.expneurol.2007.08.016. Epub 2007 Sep 5. Exp Neurol. 2007. PMID: 17931627
Linear patterns of Alzheimer's disease mutations along alpha-helices of presenilins as a tool for PS-1 model construction.
Jozwiak K, Zekanowski C, Filipek S. Jozwiak K, et al. J Neurochem. 2006 Sep;98(5):1560-72. doi: 10.1111/j.1471-4159.2006.03983.x. J Neurochem. 2006. PMID: 16923167
Modeling of ligand binding to G protein coupled receptors: cannabinoid CB1, CB2 and adrenergic β 2 AR.
Latek D, Kolinski M, Ghoshdastider U, Debinski A, Bombolewski R, Plazinska A, Jozwiak K, Filipek S. Latek D, et al. Among authors: jozwiak k. J Mol Model. 2011 Sep;17(9):2353-66. doi: 10.1007/s00894-011-0986-7. Epub 2011 Mar 2. J Mol Model. 2011. PMID: 21365223
The antidepressant-like activity of nicotine, but not of 3-furan-2-yl-N-p-tolyl-acrylamide, is regulated by the nicotinic receptor β4 subunit.
Arias HR, Targowska-Duda KM, Feuerbach D, Jozwiak K. Arias HR, et al. Among authors: jozwiak k. Neurochem Int. 2015 Aug;87:110-6. doi: 10.1016/j.neuint.2015.06.006. Epub 2015 Jun 23. Neurochem Int. 2015. PMID: 26116439
Tyrosine 308 is necessary for ligand-directed Gs protein-biased signaling of β2-adrenoceptor.
Woo AY, Jozwiak K, Toll L, Tanga MJ, Kozocas JA, Jimenez L, Huang Y, Song Y, Plazinska A, Pajak K, Paul RK, Bernier M, Wainer IW, Xiao RP. Woo AY, et al. Among authors: jozwiak k. J Biol Chem. 2014 Jul 11;289(28):19351-63. doi: 10.1074/jbc.M114.558882. Epub 2014 May 15. J Biol Chem. 2014. PMID: 24831005 Free PMC article.
Different interaction between tricyclic antidepressants and mecamylamine with the human alpha3beta4 nicotinic acetylcholine receptor ion channel.
Arias HR, Targowska-Duda KM, Feuerbach D, Sullivan CJ, Maciejewski R, Jozwiak K. Arias HR, et al. Among authors: jozwiak k. Neurochem Int. 2010 Mar;56(4):642-9. doi: 10.1016/j.neuint.2010.01.011. Epub 2010 Feb 1. Neurochem Int. 2010. PMID: 20117161
Structural and functional interaction of (±)-2-(N-tert-butylamino)-3'-iodo-4'-azidopropiophenone, a photoreactive bupropion derivative, with nicotinic acetylcholine receptors.
Arias HR, Feuerbach D, Targowska-Duda KM, Aggarwal S, Lapinsky DJ, Jozwiak K. Arias HR, et al. Among authors: jozwiak k. Neurochem Int. 2012 Dec;61(8):1433-41. doi: 10.1016/j.neuint.2012.10.011. Epub 2012 Oct 26. Neurochem Int. 2012. PMID: 23103524
Interaction of noncompetitive inhibitors with the alpha3beta2 nicotinic acetylcholine receptor investigated by affinity chromatography and molecular docking.
Jozwiak K, Ravichandran S, Collins JR, Moaddel R, Wainer IW. Jozwiak K, et al. J Med Chem. 2007 Nov 29;50(24):6279-83. doi: 10.1021/jm070784s. Epub 2007 Oct 31. J Med Chem. 2007. PMID: 17973360
Bupropion-induced inhibition of α7 nicotinic acetylcholine receptors expressed in heterologous cells and neurons from dorsal raphe nucleus and hippocampus.
Vázquez-Gómez E, Arias HR, Feuerbach D, Miranda-Morales M, Mihailescu S, Targowska-Duda KM, Jozwiak K, García-Colunga J. Vázquez-Gómez E, et al. Among authors: jozwiak k. Eur J Pharmacol. 2014 Oct 5;740:103-11. doi: 10.1016/j.ejphar.2014.06.059. Epub 2014 Jul 9. Eur J Pharmacol. 2014. PMID: 25016090
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