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The novel Hha/YmoA family of nucleoid-associated proteins: use of structural mimicry to modulate the activity of the H-NS family of proteins.
Madrid C, Balsalobre C, García J, Juárez A. Madrid C, et al. Mol Microbiol. 2007 Jan;63(1):7-14. doi: 10.1111/j.1365-2958.2006.05497.x. Epub 2006 Nov 14. Mol Microbiol. 2007. PMID: 17116239 Review.
The Hha/YmoA family of proteins is a group of conserved, low-molecular-weight proteins involved in the regulation of gene expression. ...Their mode of action is currently being analysed by studying direct binding of Hha to DNA and as a component of protein complexes …
The Hha/YmoA family of proteins is a group of conserved, low-molecular-weight proteins involved in the regulation of gene expression. …
Gene duplications in the E. coli genome: common themes among pathotypes.
Bernabeu M, Sánchez-Herrero JF, Huedo P, Prieto A, Hüttener M, Rozas J, Juárez A. Bernabeu M, et al. BMC Genomics. 2019 Apr 24;20(1):313. doi: 10.1186/s12864-019-5683-4. BMC Genomics. 2019. PMID: 31014240 Free PMC article.
This gene duplication analysis shows novel relationships between E. coli pathotypes and suggests that newly identified genes that are duplicated in a high percentage of pathogenic E. coli isolates may play a role in virulence. Our study also shows a relations …
This gene duplication analysis shows novel relationships between E. coli pathotypes and suggests that newly identified genes that are duplic …
Stringent Response and AggR-Dependent Virulence Regulation in the Enteroaggregative Escherichia coli Strain 042.
Hüttener M, Prieto A, Espelt J, Bernabeu M, Juárez A. Hüttener M, et al. Front Microbiol. 2018 Apr 10;9:717. doi: 10.3389/fmicb.2018.00717. eCollection 2018. Front Microbiol. 2018. PMID: 29692772 Free PMC article.
We show in this report that, as reported for other virulence factors, the nucleotide second messenger (p)ppGpp is needed for a high expression level of AggR. ...These results show a direct correlation between (p)ppGpp, expression of AggR and biofilm development in s …
We show in this report that, as reported for other virulence factors, the nucleotide second messenger (p)ppGpp is needed for a high e …
Biofilm modifies expression of ribonucleotide reductase genes in Escherichia coli.
Cendra Mdel M, Juárez A, Torrents E. Cendra Mdel M, et al. PLoS One. 2012;7(9):e46350. doi: 10.1371/journal.pone.0046350. Epub 2012 Sep 26. PLoS One. 2012. PMID: 23050019 Free PMC article.
Identification of two new intimin types in atypical enteropathogenic Escherichia coli.
Blanco M, Blanco JE, Dahbi G, Alonso MP, Mora A, Coira MA, Madrid C, Juárez A, Bernárdez MI, González EA, Blanco J. Blanco M, et al. Int Microbiol. 2006 Jun;9(2):103-10. Int Microbiol. 2006. PMID: 16835840
The incC Sequence Is Required for R27 Plasmid Stability.
Tassinari E, Aznar S, Urcola I, Prieto A, Hüttener M, Juárez A. Tassinari E, et al. Front Microbiol. 2016 May 3;7:629. doi: 10.3389/fmicb.2016.00629. eCollection 2016. Front Microbiol. 2016. PMID: 27199955 Free PMC article.
A high percentage of the R27-encoded open reading frames (ORFs) (66.7%) do not show similarity to any known ORFs. We performed a deletion analysis of all non-essential R27 DNA sequences to search for hitherto non-identified plasmid functions that might be required f
A high percentage of the R27-encoded open reading frames (ORFs) (66.7%) do not show similarity to any known ORFs. We performed a
MgaSpn and H-NS: Two Unrelated Global Regulators with Similar DNA-Binding Properties.
Solano-Collado V, Hüttener M, Espinosa M, Juárez A, Bravo A. Solano-Collado V, et al. Front Mol Biosci. 2016 Sep 29;3:60. doi: 10.3389/fmolb.2016.00060. eCollection 2016. Front Mol Biosci. 2016. PMID: 27747214 Free PMC article.
Bacterial pathogens thriving in the tissues and organs of their eukaryotic hosts are a well-studied example. Some of the proteins that recognize local DNA structures rather than specific nucleotide sequences act as global modulators in many bacteria, both Gram-negative and …
Bacterial pathogens thriving in the tissues and organs of their eukaryotic hosts are a well-studied example. Some of the proteins tha …
Nanoscale Electric Permittivity of Single Bacterial Cells at Gigahertz Frequencies by Scanning Microwave Microscopy.
Biagi MC, Fabregas R, Gramse G, Van Der Hofstadt M, Juárez A, Kienberger F, Fumagalli L, Gomila G. Biagi MC, et al. ACS Nano. 2016 Jan 26;10(1):280-8. doi: 10.1021/acsnano.5b04279. Epub 2015 Dec 9. ACS Nano. 2016. PMID: 26643251
To this end, calibrated complex admittance images have been obtained at ∼19 GHz and analyzed with a methodology that removes the nonlocal topographic cross-talk contributions and thus provides quantifiable intrinsic dielectric images of the bacterial cells. Results for sin …
To this end, calibrated complex admittance images have been obtained at ∼19 GHz and analyzed with a methodology that removes the nonl …
Antibiotics shaping bacterial genome: deletion of an IS91 flanked virulence determinant upon exposure to subinhibitory antibiotic concentrations.
Pedró L, Baños RC, Aznar S, Madrid C, Balsalobre C, Juárez A. Pedró L, et al. PLoS One. 2011;6(11):e27606. doi: 10.1371/journal.pone.0027606. Epub 2011 Nov 11. PLoS One. 2011. PMID: 22096603 Free PMC article.
A fluctuation test evidenced that the presence of km in the culture medium was underlying the generation of these clones. A decrease of the km concentration from 25 mg/l to 12.5 mg/l abolished the appearance of Hly(-) derivatives. ...At a km concentration of
A fluctuation test evidenced that the presence of km in the culture medium was underlying the generation of these clones. A de
A novel role for antibiotic resistance plasmids in facilitating Salmonella adaptation to non-host environments.
Paytubi S, Aznar S, Madrid C, Balsalobre C, Dillon SC, Dorman CJ, Juárez A. Paytubi S, et al. Environ Microbiol. 2014 Apr;16(4):950-62. doi: 10.1111/1462-2920.12244. Epub 2013 Sep 12. Environ Microbiol. 2014. PMID: 24024872
In the pathogenic bacterium Salmonella, plasmids of the incompatibility group HI1 account for a significant proportion of antibiotic resistance phenotypes. ...A significant number of the R27-dependent alterations in gene expression could be correlated with expressio …
In the pathogenic bacterium Salmonella, plasmids of the incompatibility group HI1 account for a significant proportion of antibiotic …
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