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RNAi-mediated gene silencing in non-human primates.
Zimmermann TS, Lee AC, Akinc A, Bramlage B, Bumcrot D, Fedoruk MN, Harborth J, Heyes JA, Jeffs LB, John M, Judge AD, Lam K, McClintock K, Nechev LV, Palmer LR, Racie T, Röhl I, Seiffert S, Shanmugam S, Sood V, Soutschek J, Toudjarska I, Wheat AJ, Yaworski E, Zedalis W, Koteliansky V, Manoharan M, Vornlocher HP, MacLachlan I. Zimmermann TS, et al. Among authors: judge ad. Nature. 2006 May 4;441(7089):111-4. doi: 10.1038/nature04688. Epub 2006 Mar 26. Nature. 2006. PMID: 16565705
Potent and persistent in vivo anti-HBV activity of chemically modified siRNAs.
Morrissey DV, Lockridge JA, Shaw L, Blanchard K, Jensen K, Breen W, Hartsough K, Machemer L, Radka S, Jadhav V, Vaish N, Zinnen S, Vargeese C, Bowman K, Shaffer CS, Jeffs LB, Judge A, MacLachlan I, Polisky B. Morrissey DV, et al. Nat Biotechnol. 2005 Aug;23(8):1002-7. doi: 10.1038/nbt1122. Epub 2005 Jul 24. Nat Biotechnol. 2005. PMID: 16041363 Free article.
siRNA and innate immunity.
Robbins M, Judge A, MacLachlan I. Robbins M, et al. Oligonucleotides. 2009 Jun;19(2):89-102. doi: 10.1089/oli.2009.0180. Oligonucleotides. 2009. PMID: 19441890 Review.
2'-O-methyl-modified RNAs act as TLR7 antagonists.
Robbins M, Judge A, Liang L, McClintock K, Yaworski E, MacLachlan I. Robbins M, et al. Mol Ther. 2007 Sep;15(9):1663-9. doi: 10.1038/sj.mt.6300240. Epub 2007 Jun 19. Mol Ther. 2007. PMID: 17579574 Free article.
28 results