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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 4
2004 1
2005 7
2006 5
2007 3
2008 4
2009 3
2010 6
2011 11
2012 10
2013 9
2014 10
2015 6
2016 4
2017 4
2018 9
2019 9
2020 6
2021 8
2022 7
2023 11
2024 13
2025 7
2026 0

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148 results

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Page 1
Brain malformations and seizures by impaired chaperonin function of TRiC.
Kraft F, Rodriguez-Aliaga P, Yuan W, Franken L, Zajt K, Hasan D, Lee TT, Flex E, Hentschel A, Innes AM, Zheng B, Julia Suh DS, Knopp C, Lausberg E, Krause J, Zhang X, Trapane P, Carroll R, McClatchey M, Fry AE, Wang L, Giesselmann S, Hoang H, Baldridge D, Silverman GA, Radio FC, Bertini E, Ciolfi A, Blood KA, de Sainte Agathe JM, Charles P, Bergant G, Čuturilo G, Peterlin B, Diderich K, Streff H, Robak L, Oegema R, van Binsbergen E, Herriges J, Saunders CJ, Maier A, Wolking S, Weber Y, Lochmüller H, Meyer S, Aleman A, Polavarapu K, Nicolas G, Goldenberg A, Guyant L, Pope K, Hehmeyer KN, Monaghan KG, Quade A, Smol T, Caumes R, Duerinckx S, Depondt C, Van Paesschen W, Rieubland C, Poloni C, Guipponi M, Arcioni S, Meuwissen M, Jansen AC, Rosenblum J, Haack TB, Bertrand M, Gerstner L, Magg J, Riess O, Schulz JB, Wagner N, Wiesmann M, Weis J, Eggermann T, Begemann M, Roos A, Häusler M, Schedl T, Tartaglia M, Bremer J, Pak SC, Frydman J, Elbracht M, Kurth I. Kraft F, et al. Among authors: frydman j. Science. 2024 Nov;386(6721):516-525. doi: 10.1126/science.adp8721. Epub 2024 Oct 31. Science. 2024. PMID: 39480921 Free PMC article.
Altered translation elongation contributes to key hallmarks of aging in the killifish brain.
Di Fraia D, Marino A, Lee JH, Kelmer Sacramento E, Baumgart M, Bagnoli S, Balla T, Schalk F, Kamrad S, Guan R, Caterino C, Giannuzzi C, Tomaz da Silva P, Sahu AK, Gut H, Siano G, Tiessen M, Terzibasi-Tozzini E, Fornasiero EF, Gagneur J, Englert C, Patil KR, Correia-Melo C, Nedialkova DD, Frydman J, Cellerino A, Ori A. Di Fraia D, et al. Among authors: frydman j. Science. 2025 Jul 31;389(6759):eadk3079. doi: 10.1126/science.adk3079. Epub 2025 Jul 31. Science. 2025. PMID: 40743332
A defective viral genome strategy elicits broad protective immunity against respiratory viruses.
Xiao Y, Lidsky PV, Shirogane Y, Aviner R, Wu CT, Li W, Zheng W, Talbot D, Catching A, Doitsh G, Su W, Gekko CE, Nayak A, Ernst JD, Brodsky L, Brodsky E, Rousseau E, Capponi S, Bianco S, Nakamura R, Jackson PK, Frydman J, Andino R. Xiao Y, et al. Among authors: frydman j. Cell. 2021 Dec 9;184(25):6037-6051.e14. doi: 10.1016/j.cell.2021.11.023. Epub 2021 Nov 18. Cell. 2021. PMID: 34852237 Free PMC article.
NAC controls nascent chain fate through tunnel sensing and chaperone action.
Lee JH, Rabl L, Gamerdinger M, Goyal V, Khakzar KM, Barbosa NM, Abramovich J, Morales-Polanco F, Köhler AK, Samatova E, Rodnina MV, Deuerling E, Frydman J. Lee JH, et al. Among authors: frydman j. Nature. 2025 Dec 22. doi: 10.1038/s41586-025-10058-2. Online ahead of print. Nature. 2025. PMID: 41430436
A hierarchical assembly pathway directs the unique subunit arrangement of TRiC/CCT.
Betancourt Moreira K, Collier MP, Leitner A, Li KH, Lachapel ILS, McCarthy F, Opoku-Nsiah KA, Morales-Polanco F, Barbosa N, Gestaut D, Samant RS, Roh SH, Frydman J. Betancourt Moreira K, et al. Among authors: frydman j. Mol Cell. 2023 Sep 7;83(17):3123-3139.e8. doi: 10.1016/j.molcel.2023.07.031. Epub 2023 Aug 24. Mol Cell. 2023. PMID: 37625406 Free PMC article.
148 results