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Detection of ubiquitinated huntingtin species in intracellular aggregates.
Juenemann K, Wiemhoefer A, Reits EA. Juenemann K, et al. Front Mol Neurosci. 2015 Jan 28;8:1. doi: 10.3389/fnmol.2015.00001. eCollection 2015. Front Mol Neurosci. 2015. PMID: 25674046 Free PMC article.
Crosstalk Between Chaperone-Mediated Protein Disaggregation and Proteolytic Pathways in Aging and Disease.
Feleciano DR, Juenemann K, Iburg M, BrĂ¡s IC, Holmberg CI, Kirstein J. Feleciano DR, et al. Among authors: juenemann k. Front Aging Neurosci. 2019 Jan 29;11:9. doi: 10.3389/fnagi.2019.00009. eCollection 2019. Front Aging Neurosci. 2019. PMID: 30760997 Free PMC article.
Cellular strategies to cope with protein aggregation.
Scior A, Juenemann K, Kirstein J. Scior A, et al. Essays Biochem. 2016 Oct 15;60(2):153-161. doi: 10.1042/EBC20160002. Essays Biochem. 2016. PMID: 27744331 Review.
Expanded polyglutamine-containing N-terminal huntingtin fragments are entirely degraded by mammalian proteasomes.
Juenemann K, Schipper-Krom S, Wiemhoefer A, Kloss A, Sanz Sanz A, Reits EA. Juenemann K, et al. J Biol Chem. 2013 Sep 20;288(38):27068-84. doi: 10.1074/jbc.M113.486076. Epub 2013 Aug 1. J Biol Chem. 2013. PMID: 23908352 Free PMC article.
The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.
Gillis J, Schipper-Krom S, Juenemann K, Gruber A, Coolen S, van den Nieuwendijk R, van Veen H, Overkleeft H, Goedhart J, Kampinga HH, Reits EA. Gillis J, et al. J Biol Chem. 2013 Jun 14;288(24):17225-37. doi: 10.1074/jbc.M112.421685. Epub 2013 Apr 23. J Biol Chem. 2013. PMID: 23612975 Free PMC article.
The Ubiquitin-Proteasome System in Huntington's Disease: Are Proteasomes Impaired, Initiators of Disease, or Coming to the Rescue?
Schipper-Krom S, Juenemann K, Reits EA. Schipper-Krom S, et al. Biochem Res Int. 2012;2012:837015. doi: 10.1155/2012/837015. Epub 2012 Sep 24. Biochem Res Int. 2012. PMID: 23050151 Free PMC article.
Global Proteome and Ubiquitinome Changes in the Soluble and Insoluble Fractions of Q175 Huntington Mice Brains.
Sap KA, Guler AT, Bezstarosti K, Bury AE, Juenemann K, Demmers JAA, Reits EA. Sap KA, et al. Among authors: juenemann k. Mol Cell Proteomics. 2019 Sep;18(9):1705-1720. doi: 10.1074/mcp.RA119.001486. Epub 2019 May 28. Mol Cell Proteomics. 2019. PMID: 31138642 Free PMC article.
Dynamic recruitment of ubiquitin to mutant huntingtin inclusion bodies.
Juenemann K, Jansen AHP, van Riel L, Merkx R, Mulder MPC, An H, Statsyuk A, Kirstein J, Ovaa H, Reits EA. Juenemann K, et al. Sci Rep. 2018 Jan 23;8(1):1405. doi: 10.1038/s41598-018-19538-0. Sci Rep. 2018. PMID: 29362455 Free PMC article.
Dynamic recruitment of active proteasomes into polyglutamine initiated inclusion bodies.
Schipper-Krom S, Juenemann K, Jansen AH, Wiemhoefer A, van den Nieuwendijk R, Smith DL, Hink MA, Bates GP, Overkleeft H, Ovaa H, Reits E. Schipper-Krom S, et al. FEBS Lett. 2014 Jan 3;588(1):151-9. doi: 10.1016/j.febslet.2013.11.023. Epub 2013 Nov 26. FEBS Lett. 2014. PMID: 24291262
Alternative macroautophagic pathways.
Juenemann K, Reits EA. Juenemann K, et al. Int J Cell Biol. 2012;2012:189794. doi: 10.1155/2012/189794. Epub 2012 Mar 27. Int J Cell Biol. 2012. PMID: 22536246 Free PMC article.
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