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The shedding activity of ADAM17 is sequestered in lipid rafts.
Tellier E, Canault M, Rebsomen L, Bonardo B, Juhan-Vague I, Nalbone G, Peiretti F. Tellier E, et al. Exp Cell Res. 2006 Dec 10;312(20):3969-80. doi: 10.1016/j.yexcr.2006.08.027. Epub 2006 Sep 5. Exp Cell Res. 2006. PMID: 17010968
The TNF alpha converting enzyme (TACE/ADAM17) is expressed in the atherosclerotic lesions of apolipoprotein E-deficient mice: possible contribution to elevated plasma levels of soluble TNF alpha receptors.
Canault M, Peiretti F, Kopp F, Bonardo B, Bonzi MF, Coudeyre JC, Alessi MC, Juhan-Vague I, Nalbone G. Canault M, et al. Atherosclerosis. 2006 Jul;187(1):82-91. doi: 10.1016/j.atherosclerosis.2005.08.031. Epub 2005 Oct 7. Atherosclerosis. 2006. PMID: 16214147
Polymorphisms of the tumor necrosis factor-alpha (TNF) and the TNF-alpha converting enzyme (TACE/ADAM17) genes in relation to cardiovascular mortality: the AtheroGene study.
Morange PE, Tregouet DA, Godefroy T, Saut N, Bickel C, Rupprecht HJ, Lackner K, Barbaux S, Poirier O, Peiretti F, Nalbone G, Juhan-Vague I, Blankenberg S, Tiret L. Morange PE, et al. J Mol Med (Berl). 2008 Oct;86(10):1153-61. doi: 10.1007/s00109-008-0375-6. Epub 2008 Jul 4. J Mol Med (Berl). 2008. PMID: 18600307
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