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A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function.
Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR, Bos SD, Deelen J, den Heijer M, Freathy RM, Lahti J, Liu C, Lopez LM, Nolte IM, O'Connell JR, Tanaka T, Trompet S, Arnold A, Bandinelli S, Beekman M, Böhringer S, Brown SJ, Buckley BM, Camaschella C, de Craen AJ, Davies G, de Visser MC, Ford I, Forsen T, Frayling TM, Fugazzola L, Gögele M, Hattersley AT, Hermus AR, Hofman A, Houwing-Duistermaat JJ, Jensen RA, Kajantie E, Kloppenburg M, Lim EM, Masciullo C, Mariotti S, Minelli C, Mitchell BD, Nagaraja R, Netea-Maier RT, Palotie A, Persani L, Piras MG, Psaty BM, Räikkönen K, Richards JB, Rivadeneira F, Sala C, Sabra MM, Sattar N, Shields BM, Soranzo N, Starr JM, Stott DJ, Sweep FC, Usala G, van der Klauw MM, van Heemst D, van Mullem A, Vermeulen SH, Visser WE, Walsh JP, Westendorp RG, Widen E, Zhai G, Cucca F, Deary IJ, Eriksson JG, Ferrucci L, Fox CS, Jukema JW, Kiemeney LA, Pramstaller PP, Schlessinger D, Shuldiner AR, Slagboom EP, Uitterlinden AG, Vaidya B, Visser TJ, Wolffenbuttel BH, Meulenbelt I, Rotter JI, Spector TD, Hicks AA, Toniolo D, Sanna S, Peeters RP, Naitza S. Porcu E, et al. Among authors: jukema jw. PLoS Genet. 2013;9(2):e1003266. doi: 10.1371/journal.pgen.1003266. Epub 2013 Feb 7. PLoS Genet. 2013. PMID: 23408906 Free PMC article.
Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study.
Trompet S, Pons D, DE Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Cobbe SM, Bollen EL, Buckley BM, Ford I, Hyland M, Gaw A, Macfarlane PW, Packard CJ, Norrie J, Perry IJ, Stott DJ, Sweeney BJ, Twomey C, Westendorp RG, Jukema JW. Trompet S, et al. Among authors: jukema jw. Ann N Y Acad Sci. 2007 Apr;1100:189-98. doi: 10.1196/annals.1395.018. Ann N Y Acad Sci. 2007. PMID: 17460178 Clinical Trial.
Genetic variation at the LDL receptor and HMG-CoA reductase gene loci, lipid levels, statin response, and cardiovascular disease incidence in PROSPER.
Polisecki E, Muallem H, Maeda N, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Westendorp RG, de Craen AJ, Buckley BM, Ordovas JM, Schaefer EJ; Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Investigators. Polisecki E, et al. Among authors: jukema jw. Atherosclerosis. 2008 Sep;200(1):109-14. doi: 10.1016/j.atherosclerosis.2007.12.004. Epub 2008 Feb 7. Atherosclerosis. 2008. PMID: 18261733 Free PMC article. Clinical Trial.
Genetic variation at the PCSK9 locus moderately lowers low-density lipoprotein cholesterol levels, but does not significantly lower vascular disease risk in an elderly population.
Polisecki E, Peter I, Robertson M, McMahon AD, Ford I, Packard C, Shepherd J, Jukema JW, Blauw GJ, Westendorp RG, de Craen AJ, Trompet S, Buckley BM, Murphy MB, Ordovas JM, Schaefer EJ; PROSPER Study Group. Polisecki E, et al. Among authors: jukema jw. Atherosclerosis. 2008 Sep;200(1):95-101. doi: 10.1016/j.atherosclerosis.2007.12.005. Epub 2008 Feb 8. Atherosclerosis. 2008. PMID: 18262190 Free PMC article. Clinical Trial.
Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study.
Trompet S, de Craen AJ, Slagboom P, Shepherd J, Blauw GJ, Murphy MB, Bollen EL, Buckley BM, Ford I, Gaw A, Macfarlane PW, Packard CJ, Stott DJ, Westendorp RG, Jukema JW; PROSPER Group. Trompet S, et al. Among authors: jukema jw. Exp Gerontol. 2008 Aug;43(8):801-5. doi: 10.1016/j.exger.2008.04.006. Epub 2008 Apr 22. Exp Gerontol. 2008. PMID: 18504081
Statins and blood pressure.
Trompet S, Jukema JW, Ford I, Shepherd J, Gussekloo J, Buckley BM, Westendorp RG, de Craen AJ. Trompet S, et al. Among authors: jukema jw. Arch Intern Med. 2008 Nov 24;168(21):2383. doi: 10.1001/archinte.168.21.2383-a. Arch Intern Med. 2008. PMID: 19029506 No abstract available.
1,089 results