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Adoptive cellular therapy: a race to the finish line.
June CH, Riddell SR, Schumacher TN. June CH, et al. Sci Transl Med. 2015 Mar 25;7(280):280ps7. doi: 10.1126/scitranslmed.aaa3643. Sci Transl Med. 2015. PMID: 25810311 Review.
Adoptive transfer of simian immunodeficiency virus (SIV) naïve autologous CD4(+) cells to macaques chronically infected with SIV is sufficient to induce long-term nonprogressor status.
Villinger F, Brice GT, Mayne AE, Bostik P, Mori K, June CH, Ansari AA. Villinger F, et al. Blood. 2002 Jan 15;99(2):590-9. doi: 10.1182/blood.v99.2.590. Blood. 2002. PMID: 11781243
Adoptive transfer of costimulated CD4+ T cells induces expansion of peripheral T cells and decreased CCR5 expression in HIV infection.
Levine BL, Bernstein WB, Aronson NE, Schlienger K, Cotte J, Perfetto S, Humphries MJ, Ratto-Kim S, Birx DL, Steffens C, Landay A, Carroll RG, June CH. Levine BL, et al. Nat Med. 2002 Jan;8(1):47-53. doi: 10.1038/nm0102-47. Nat Med. 2002. PMID: 11786906 Clinical Trial.
Ex vivo expansion of polyclonal and antigen-specific cytotoxic T lymphocytes by artificial APCs expressing ligands for the T-cell receptor, CD28 and 4-1BB.
Maus MV, Thomas AK, Leonard DG, Allman D, Addya K, Schlienger K, Riley JL, June CH. Maus MV, et al. Nat Biotechnol. 2002 Feb;20(2):143-8. doi: 10.1038/nbt0202-143. Nat Biotechnol. 2002. PMID: 11821859
Adoptive transfer of costimulated T cells induces lymphocytosis in patients with relapsed/refractory non-Hodgkin lymphoma following CD34+-selected hematopoietic cell transplantation.
Laport GG, Levine BL, Stadtmauer EA, Schuster SJ, Luger SM, Grupp S, Bunin N, Strobl FJ, Cotte J, Zheng Z, Gregson B, Rivers P, Vonderheide RH, Liebowitz DN, Porter DL, June CH. Laport GG, et al. Blood. 2003 Sep 15;102(6):2004-13. doi: 10.1182/blood-2003-01-0095. Epub 2003 May 22. Blood. 2003. PMID: 12763934 Clinical Trial.
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