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The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage.
Larsen DH, Hari F, Clapperton JA, Gwerder M, Gutsche K, Altmeyer M, Jungmichel S, Toledo LI, Fink D, Rask MB, Grøfte M, Lukas C, Nielsen ML, Smerdon SJ, Lukas J, Stucki M. Larsen DH, et al. Among authors: jungmichel s. Nat Cell Biol. 2014 Aug;16(8):792-803. doi: 10.1038/ncb3007. Epub 2014 Jul 27. Nat Cell Biol. 2014. PMID: 25064736 Free PMC article.
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.
Mooser C, Symeonidou IE, Leimbacher PA, Ribeiro A, Shorrocks AK, Jungmichel S, Larsen SC, Knechtle K, Jasrotia A, Zurbriggen D, Jeanrenaud A, Leikauf C, Fink D, Nielsen ML, Blackford AN, Stucki M. Mooser C, et al. Among authors: jungmichel s. Nat Commun. 2020 Jan 8;11(1):123. doi: 10.1038/s41467-019-13981-x. Nat Commun. 2020. PMID: 31913317 Free PMC article.
MDC1: The art of keeping things in focus.
Jungmichel S, Stucki M. Jungmichel S, et al. Chromosoma. 2010 Aug;119(4):337-49. doi: 10.1007/s00412-010-0266-9. Epub 2010 Mar 12. Chromosoma. 2010. PMID: 20224865 Free article. Review.
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