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Membrane proteins of the endoplasmic reticulum induce high-curvature tubules.
Hu J, Shibata Y, Voss C, Shemesh T, Li Z, Coughlin M, Kozlov MM, Rapoport TA, Prinz WA. Hu J, et al. Science. 2008 Feb 29;319(5867):1247-50. doi: 10.1126/science.1153634. Science. 2008. PMID: 18309084
The tubular structure of the endoplasmic reticulum (ER) appears to be generated by integral membrane proteins, the reticulons and a protein family consisting of DP1 in mammals and Yop1p in yeast. Here, individual members of these families were found to be sufficient to gen …
The tubular structure of the endoplasmic reticulum (ER) appears to be generated by integral membrane proteins, the reticulons and a p …
The reticulon and DP1/Yop1p proteins form immobile oligomers in the tubular endoplasmic reticulum.
Shibata Y, Voss C, Rist JM, Hu J, Rapoport TA, Prinz WA, Voeltz GK. Shibata Y, et al. Among authors: hu j. J Biol Chem. 2008 Jul 4;283(27):18892-904. doi: 10.1074/jbc.M800986200. Epub 2008 Apr 28. J Biol Chem. 2008. PMID: 18442980 Free PMC article.
We recently identified a class of membrane proteins, the reticulons and DP1/Yop1p, which shape the tubular endoplasmic reticulum (ER) in yeast and mammalian cells. ...To understand how they promote tubule formation, we characterized their behavior in cellular membranes …
We recently identified a class of membrane proteins, the reticulons and DP1/Yop1p, which shape the tubular endoplasmic reticulum (ER) …