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Differential effects of inhibiting chitin and 1,3-{beta}-D-glucan synthesis in ras and calcineurin mutants of Aspergillus fumigatus.
Fortwendel JR, Juvvadi PR, Pinchai N, Perfect BZ, Alspaugh JA, Perfect JR, Steinbach WJ. Fortwendel JR, et al. Antimicrob Agents Chemother. 2009 Feb;53(2):476-82. doi: 10.1128/AAC.01154-08. Epub 2008 Nov 17. Antimicrob Agents Chemother. 2009. PMID: 19015336 Free PMC article.
Transcriptional regulation of chitin synthases by calcineurin controls paradoxical growth of Aspergillus fumigatus in response to caspofungin.
Fortwendel JR, Juvvadi PR, Perfect BZ, Rogg LE, Perfect JR, Steinbach WJ. Fortwendel JR, et al. Antimicrob Agents Chemother. 2010 Apr;54(4):1555-63. doi: 10.1128/AAC.00854-09. Epub 2010 Feb 1. Antimicrob Agents Chemother. 2010. PMID: 20124000 Free PMC article.
Newer combination antifungal therapies for invasive aspergillosis.
Steinbach WJ, Juvvadi PR, Fortwendel JR, Rogg LE. Steinbach WJ, et al. Med Mycol. 2011 Apr;49 Suppl 1(0 1):S77-81. doi: 10.3109/13693786.2010.499374. Epub 2010 Jul 7. Med Mycol. 2011. PMID: 20608784 Free PMC article. Review.
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