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Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance.
König J, Nies AT, Cui Y, Leier I, Keppler D. König J, et al. Biochim Biophys Acta. 1999 Dec 6;1461(2):377-94. doi: 10.1016/s0005-2736(99)00169-8. Biochim Biophys Acta. 1999. PMID: 10581368 Review.
cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats.
Büchler M, König J, Brom M, Kartenbeck J, Spring H, Horie T, Keppler D. Büchler M, et al. Among authors: konig j. J Biol Chem. 1996 Jun 21;271(25):15091-8. doi: 10.1074/jbc.271.25.15091. J Biol Chem. 1996. PMID: 8662992
Hepatic canalicular membrane 5: Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver.
Keppler D, Konig J. Keppler D, et al. Among authors: konig j. FASEB J. 1997 Jun;11(7):509-16. doi: 10.1096/fasebj.11.7.9212074. FASEB J. 1997. PMID: 9212074 Review.
Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules.
Schaub TP, Kartenbeck J, König J, Vogel O, Witzgall R, Kriz W, Keppler D. Schaub TP, et al. Among authors: konig j. J Am Soc Nephrol. 1997 Aug;8(8):1213-21. J Am Soc Nephrol. 1997. PMID: 9259347
The canalicular multidrug resistance protein, cMRP/MRP2, a novel conjugate export pump expressed in the apical membrane of hepatocytes.
Keppler D, König J, Büchler M. Keppler D, et al. Among authors: konig j. Adv Enzyme Regul. 1997;37:321-33. doi: 10.1016/s0065-2571(96)00013-1. Adv Enzyme Regul. 1997. PMID: 9381978
Multidrug resistance protein-mediated transport of chlorambucil and melphalan conjugated to glutathione.
Barnouin K, Leier I, Jedlitschky G, Pourtier-Manzanedo A, König J, Lehmann WD, Keppler D. Barnouin K, et al. Among authors: konig j. Br J Cancer. 1998;77(2):201-9. doi: 10.1038/bjc.1998.34. Br J Cancer. 1998. PMID: 9460989 Free PMC article.
ATP-dependent transport of glutathione S-conjugates by the multidrug resistance protein MRP1 and its apical isoform MRP2.
Keppler D, Leier I, Jedlitschky G, König J. Keppler D, et al. Among authors: konig j. Chem Biol Interact. 1998 Apr 24;111-112:153-61. doi: 10.1016/s0009-2797(97)00158-0. Chem Biol Interact. 1998. PMID: 9679551 Review.
Human mast cells secreting leukotriene C4 express the MRP1 gene-encoded conjugate export pump.
Bartosz G, König J, Keppler D, Hagmann W. Bartosz G, et al. Among authors: konig j. Biol Chem. 1998 Aug-Sep;379(8-9):1121-6. doi: 10.1515/bchm.1998.379.8-9.1121. Biol Chem. 1998. PMID: 9792445
Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane.
König J, Rost D, Cui Y, Keppler D. König J, et al. Hepatology. 1999 Apr;29(4):1156-63. doi: 10.1002/hep.510290404. Hepatology. 1999. PMID: 10094960
Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug resistance protein, MRP2, permanently expressed in human and canine cells.
Cui Y, König J, Buchholz JK, Spring H, Leier I, Keppler D. Cui Y, et al. Among authors: konig j. Mol Pharmacol. 1999 May;55(5):929-37. Mol Pharmacol. 1999. PMID: 10220572
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