Kühnast B - Search Results

1

General method to label antisense oligonucleotides with radioactive halogens for pharmacological and imaging studies.

Kühnast B, Dollé F, Terrazzino S, Rousseau B, Loc'h C, Vaufrey F, Hinnen F, Doignon I, Pillon F, David C, Crouzel C, Tavitian B. Kühnast B, et al. Bioconjug Chem. 2000 Sep-Oct;11(5):627-36. doi: 10.1021/bc990183i. Bioconjug Chem. 2000. PMID: 10995205

2

In vivo imaging of oligonucleotides with positron emission tomography.

Tavitian B, Terrazzino S, Kühnast B, Marzabal S, Stettler O, Dollé F, Deverre JR, Jobert A, Hinnen F, Bendriem B, Crouzel C, Di Giamberardino L. Tavitian B, et al. Among authors: kuhnast b. Nat Med. 1998 Apr;4(4):467-71. doi: 10.1038/nm0498-467. Nat Med. 1998. PMID: 9546795 No abstract available.

3

Characterization of a synthetic anionic vector for oligonucleotide delivery using in vivo whole body dynamic imaging.

Tavitian B, Marzabal S, Boutet V, Kühnast B, Terrazzino S, Moynier M, Dollé F, Deverre JR, Thierry AR. Tavitian B, et al. Among authors: kuhnast b. Pharm Res. 2002 Apr;19(4):367-76. doi: 10.1023/a:1015133205457. Pharm Res. 2002. PMID: 12033366

4

Design and synthesis of a new [18F]fluoropyridine-based haloacetamide reagent for the labeling of oligonucleotides: 2-bromo-N-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]acetamide.

Kuhnast B, de Bruin B, Hinnen F, Tavitian B, Dollé F. Kuhnast B, et al. Bioconjug Chem. 2004 May-Jun;15(3):617-27. doi: 10.1021/bc049979u. Bioconjug Chem. 2004. PMID: 15149190

5

In vivo biodistribution and pharmacokinetics of 18F-labelled Spiegelmers: a new class of oligonucleotidic radiopharmaceuticals.

Boisgard R, Kuhnast B, Vonhoff S, Younes C, Hinnen F, Verbavatz JM, Rousseau B, Fürste JP, Wlotzka B, Dollé F, Klussmann S, Tavitian B. Boisgard R, et al. Among authors: kuhnast b. Eur J Nucl Med Mol Imaging. 2005 Apr;32(4):470-7. doi: 10.1007/s00259-004-1669-8. Epub 2004 Dec 22. Eur J Nucl Med Mol Imaging. 2005. PMID: 15614506

6

1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins.

de Bruin B, Kuhnast B, Hinnen F, Yaouancq L, Amessou M, Johannes L, Samson A, Boisgard R, Tavitian B, Dollé F. de Bruin B, et al. Among authors: kuhnast b. Bioconjug Chem. 2005 Mar-Apr;16(2):406-20. doi: 10.1021/bc0497463. Bioconjug Chem. 2005. PMID: 15769096

7

Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.

Josserand V, Pélerin H, de Bruin B, Jego B, Kuhnast B, Hinnen F, Ducongé F, Boisgard R, Beuvon F, Chassoux F, Daumas-Duport C, Ezan E, Dollé F, Mabondzo A, Tavitian B. Josserand V, et al. Among authors: kuhnast b. J Pharmacol Exp Ther. 2006 Jan;316(1):79-86. doi: 10.1124/jpet.105.089102. Epub 2005 Oct 6. J Pharmacol Exp Ther. 2006. PMID: 16210395

8

Synthesis and radiolabeling of N-[4-[4-(2-[11C]methoxyphenyl)piperazin-1-yl]butyl]benzo[b]thiophene-2-carboxamide -- a potential radiotracer for D3 receptor imaging with PET.

Kuhnast B, Valette H, Besret L, Demphel S, Coulon C, Ottaviani M, Guillermier M, Bottlaender M, Dollé F. Kuhnast B, et al. Nucl Med Biol. 2006 Aug;33(6):785-95. doi: 10.1016/j.nucmedbio.2006.05.007. Epub 2006 Jul 18. Nucl Med Biol. 2006. PMID: 16934697

9

In vivo imaging of brain lesions with [(11)C]CLINME, a new PET radioligand of peripheral benzodiazepine receptors.

Boutin H, Chauveau F, Thominiaux C, Kuhnast B, Grégoire MC, Jan S, Trebossen R, Dollé F, Tavitian B, Mattner F, Katsifis A. Boutin H, et al. Among authors: kuhnast b. Glia. 2007 Nov 1;55(14):1459-68. doi: 10.1002/glia.20562. Glia. 2007. PMID: 17680643

10

Molecular imaging study on in vivo distribution and pharmacokinetics of modified small interfering RNAs (siRNAs).

Viel T, Boisgard R, Kuhnast B, Jego B, Siquier-Pernet K, Hinnen F, Dollé F, Tavitian B. Viel T, et al. Among authors: kuhnast b. Oligonucleotides. 2008 Sep;18(3):201-12. doi: 10.1089/oli.2008.0133. Oligonucleotides. 2008. PMID: 18729822

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