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Year Number of Results
1976 1
1978 1
1987 1
1999 1
2002 1
2006 1
2007 1
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2013 1
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2021 1
2023 2
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Page 1
[Structure-activity relationship of novel vitamin K analogues as steroid and xenobiotic receptor (SXR) agonists].
Suhara Y, Motoyoshi S, Hirota Y, Sawada N, Nakagawa K, Tokiwa H, Okano T. Suhara Y, et al. Among authors: motoyoshi s. Yakugaku Zasshi. 2012;132(8):881-6. doi: 10.1248/yakushi.132.881. Yakugaku Zasshi. 2012. PMID: 22864345 Free article. Review. Japanese.
Vitamin K2 is a ligand for a nuclear receptor, steroid and xenobiotic receptor (SXR), that induces the gene expressions of CYP3A4. We synthesized new vitamin K analogues with the same isoprene side chains symmetrically introduced at the 2 and 3 positions of 1,4-naphthoquin …
Vitamin K2 is a ligand for a nuclear receptor, steroid and xenobiotic receptor (SXR), that induces the gene expressions of CYP3A4. We synthe …
Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.
Nagasawa S, Kuze Y, Maeda I, Kojima Y, Motoyoshi A, Onishi T, Iwatani T, Yokoe T, Koike J, Chosokabe M, Kubota M, Seino H, Suzuki A, Seki M, Tsuchihara K, Inoue E, Tsugawa K, Ohta T, Suzuki Y. Nagasawa S, et al. Among authors: motoyoshi a. Commun Biol. 2021 Apr 1;4(1):438. doi: 10.1038/s42003-021-01959-9. Commun Biol. 2021. PMID: 33795819 Free PMC article.
Interaction of subunits of polypeptide chain elongation factor I from pig liver. Formation of EF-1alpha.EF-1betagamma and EF-1beta complexes.
Nagata S, Motoyoshi K, Iwasaki K. Nagata S, et al. Among authors: motoyoshi k. J Biochem. 1978 Feb;83(2):423-9. doi: 10.1093/oxfordjournals.jbchem.a131929. J Biochem. 1978. PMID: 632230 Free article.
In the preceding papers, we showed that one of the two complementar factors of polypeptide chain elongation factor 1 (EF-1) from pig liver, EF-1alpha, functionally corresponds to bacterial EF-Tu (Nagata, S., Iwasaki, K., and Kaziro, Y. (1976) Arch. Biochem. Biophys. 172, 1 …
In the preceding papers, we showed that one of the two complementar factors of polypeptide chain elongation factor 1 (EF-1) from pig liver, …
Insulin potentiates inhibitory synaptic currents between fast-spiking and pyramidal neurons in the rat insular cortex.
Nakaya Y, Kosukegawa S, Kobayashi S, Hirose K, Kitano K, Mayahara K, Takei H, Motoyoshi M, Kobayashi M. Nakaya Y, et al. Among authors: motoyoshi m. Neuropharmacology. 2023 Nov 1;238:109649. doi: 10.1016/j.neuropharm.2023.109649. Epub 2023 Jun 30. Neuropharmacology. 2023. PMID: 37393988
Insulin had little effect on uIPSCs under the coapplication of S961, an insulin receptor antagonist, or lavendustin A, an inhibitor of tyrosine kinase. The PI3-K inhibitor wortmannin or the PKB/Akt inhibitors, deguelin and Akt inhibitor VIII, blocked the insulin-induced en …
Insulin had little effect on uIPSCs under the coapplication of S961, an insulin receptor antagonist, or lavendustin A, an inhibitor of tyros …
Safety and Effectiveness of Lenvatinib in Patients with Unresectable Hepatocellular Carcinoma in Real-World Clinical Practice: An Observational Post-Marketing Study in Japan.
Furuse J, Izumi N, Motomura K, Inaba Y, Katamura Y, Kondo Y, Yabushita K, Motoyoshi K, Kudo M. Furuse J, et al. Among authors: motoyoshi k. Drugs Real World Outcomes. 2023 Jun;10(2):195-205. doi: 10.1007/s40801-022-00348-w. Epub 2023 Jan 5. Drugs Real World Outcomes. 2023. PMID: 36602748 Free PMC article.
Synthesis of new vitamin K analogues as steroid and xenobiotic receptor (SXR) agonists: insights into the biological role of the side chain part of vitamin K.
Suhara Y, Watanabe M, Motoyoshi S, Nakagawa K, Wada A, Takeda K, Takahashi K, Tokiwa H, Okano T. Suhara Y, et al. Among authors: motoyoshi s. J Med Chem. 2011 Jul 14;54(13):4918-22. doi: 10.1021/jm200201k. Epub 2011 Jun 20. J Med Chem. 2011. PMID: 21618996
Vitamin K(2) has been demonstrated to induce gene expression related to bone formation through a nuclear steroid and xenobiotic receptor (SXR). We synthesized new vitamin K analogues with the same isoprene side chains symmetrically introduced at the 2 and 3 position …
Vitamin K(2) has been demonstrated to induce gene expression related to bone formation through a nuclear steroid and xenobiotic recep …
Cloning and characterization of novel snake venom proteins that block smooth muscle contraction.
Yamazaki Y, Koike H, Sugiyama Y, Motoyoshi K, Wada T, Hishinuma S, Mita M, Morita T. Yamazaki Y, et al. Among authors: motoyoshi k. Eur J Biochem. 2002 Jun;269(11):2708-15. doi: 10.1046/j.1432-1033.2002.02940.x. Eur J Biochem. 2002. PMID: 12047379 Free article.
Ablomin blocked contraction of rat tail arterial smooth muscle elicited by high K+-induced depolarization in the 0.1-1 microm range, but did not block caffeine-stimulated contraction. ...Two of these homologous proteins, triflin and latisemin, also inhibited high K+ …
Ablomin blocked contraction of rat tail arterial smooth muscle elicited by high K+-induced depolarization in the 0.1-1 microm range, …
Continuous Compressive Force Induces Differentiation of Osteoclasts with High Levels of Inorganic Dissolution.
Matsuike R, Nakai K, Tanaka H, Ozaki M, Kanda M, Nagasaki M, Shibata C, Mayahara K, Tanabe N, Koshi R, Nakajima A, Kawato T, Maeno M, Shimizu N, Motoyoshi M. Matsuike R, et al. Among authors: motoyoshi m. Med Sci Monit. 2019 May 26;25:3902-3909. doi: 10.12659/MSM.913674. Med Sci Monit. 2019. PMID: 31129676 Free PMC article.
Matrix metalloproteinase-9 expression decreased and cathepsin K expression increased slightly by the continuous application of compressive force. ...
Matrix metalloproteinase-9 expression decreased and cathepsin K expression increased slightly by the continuous application of compre …
Hepatitis C virus-related symptoms, but not quality of life, were improved by treatment with direct-acting antivirals.
Ichikawa T, Miyaaki H, Miuma S, Taura N, Motoyoshi Y, Akahoshi H, Nakamura S, Nakamura J, Takahashi Y, Honda T, Yajima H, Uehara R, Hino N, Narita S, Tanaka H, Sasaki S, Nakao K. Ichikawa T, et al. Among authors: motoyoshi y. Hepatol Res. 2018 Feb;48(3):E232-E239. doi: 10.1111/hepr.12974. Epub 2017 Nov 13. Hepatol Res. 2018. PMID: 28837746
The PROs measured at the start of treatment and 1 year after the start of treatment were cirrhosis-related symptom score (CSS), presence of restless legs syndrome (RLS), Epworth sleepiness scale (ESS), Pittsburg sleep quality index (PSQI), Kessler 6 score (K-6), and the SF …
The PROs measured at the start of treatment and 1 year after the start of treatment were cirrhosis-related symptom score (CSS), presence of …
Purification and properties of a new polypeptide chain elongation factor, EF-1beta, from pig liver.
Iwasaki K, Motoyoshi K, Nagata S, Kaziro Y. Iwasaki K, et al. Among authors: motoyoshi k. J Biol Chem. 1976 Mar 25;251(6):1843-5. J Biol Chem. 1976. PMID: 1254599 Free article.
Eukaryotic polypeptide elongation factor 1 (EF-1) from pig liver has been resolved into two complementary factors, EF-1alpha and EF-1beta (Iwasaki, K., Mizumoto, K., Tanka, M., and Kaziro, Y. (1973) J. Biochem. (Tokyo) 74, 849). This paper describes the procedures f …
Eukaryotic polypeptide elongation factor 1 (EF-1) from pig liver has been resolved into two complementary factors, EF-1alpha and EF-1beta (I …
14 results