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Year Number of Results
2015 4
2016 1
2017 6
2018 4
2019 6
2021 0
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18 results
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Page 1
CRISPR Gene Editing in the Kidney.
Cruz NM, Freedman BS. Cruz NM, et al. Am J Kidney Dis. 2018 Jun;71(6):874-883. doi: 10.1053/j.ajkd.2018.02.347. Epub 2018 Mar 30. Am J Kidney Dis. 2018. PMID: 29606501 Free PMC article. Review.
Differentiation of human kidney organoids from pluripotent stem cells.
Cruz NM, Freedman BS. Cruz NM, et al. Methods Cell Biol. 2019;153:133-150. doi: 10.1016/bs.mcb.2019.05.003. Epub 2019 Jun 19. Methods Cell Biol. 2019. PMID: 31395376 Review.
Nephron organoids derived from human pluripotent stem cells model kidney development and injury.
Morizane R, Lam AQ, Freedman BS, Kishi S, Valerius MT, Bonventre JV. Morizane R, et al. Nat Biotechnol. 2015 Nov;33(11):1193-200. doi: 10.1038/nbt.3392. Nat Biotechnol. 2015. PMID: 26458176 Free PMC article.
High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping.
Czerniecki SM, Cruz NM, Harder JL, Menon R, Annis J, Otto EA, Gulieva RE, Islas LV, Kim YK, Tran LM, Martins TJ, Pippin JW, Fu H, Kretzler M, Shankland SJ, Himmelfarb J, Moon RT, Paragas N, Freedman BS. Czerniecki SM, et al. Cell Stem Cell. 2018 Jun 1;22(6):929-940.e4. doi: 10.1016/j.stem.2018.04.022. Epub 2018 May 17. Cell Stem Cell. 2018. PMID: 29779890 Free PMC article.
Organoid single cell profiling identifies a transcriptional signature of glomerular disease.
Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, Freedman BS, Kretzler M; European Renal cDNA Bank (ERCB); Nephrotic Syndrome Study Network (NEPTUNE). Harder JL, et al. JCI Insight. 2019 Jan 10;4(1):e122697. doi: 10.1172/jci.insight.122697. JCI Insight. 2019. PMID: 30626756 Free PMC article.
Producing Purer Podocytes.
Freedman BS. Freedman BS. J Am Soc Nephrol. 2019 Feb;30(2):183-184. doi: 10.1681/ASN.2018101045. Epub 2019 Jan 11. J Am Soc Nephrol. 2019. PMID: 30635374 Free PMC article. No abstract available.
Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease.
Cruz NM, Song X, Czerniecki SM, Gulieva RE, Churchill AJ, Kim YK, Winston K, Tran LM, Diaz MA, Fu H, Finn LS, Pei Y, Himmelfarb J, Freedman BS. Cruz NM, et al. Nat Mater. 2017 Nov;16(11):1112-1119. doi: 10.1038/nmat4994. Epub 2017 Oct 2. Nat Mater. 2017. PMID: 28967916 Free PMC article.
Graft immaturity and safety concerns in transplanted human kidney organoids.
Nam SA, Seo E, Kim JW, Kim HW, Kim HL, Kim K, Kim TM, Ju JH, Gomez IG, Uchimura K, Humphreys BD, Yang CW, Lee JY, Kim J, Cho DW, Freedman BS, Kim YK. Nam SA, et al. Exp Mol Med. 2019 Nov 28;51(11):1-13. doi: 10.1038/s12276-019-0336-x. Exp Mol Med. 2019. PMID: 31776328 Free PMC article.
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.
Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, Musunuru K, McNagny KM, Steinman TI, Zhou J, Lerou PH, Bonventre JV. Freedman BS, et al. Nat Commun. 2015 Oct 23;6:8715. doi: 10.1038/ncomms9715. Nat Commun. 2015. PMID: 26493500 Free PMC article.
Building Scaffolds To Rebuild Kidneys.
Freedman BS, Ratner B. Freedman BS, et al. ACS Cent Sci. 2019 Mar 27;5(3):380-382. doi: 10.1021/acscentsci.9b00099. Epub 2019 Feb 27. ACS Cent Sci. 2019. PMID: 30937364 Free PMC article. No abstract available.
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