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MAIT cells are imprinted by the microbiota in early life and promote tissue repair.
Constantinides MG, Link VM, Tamoutounour S, Wong AC, Perez-Chaparro PJ, Han SJ, Chen YE, Li K, Farhat S, Weckel A, Krishnamurthy SR, Vujkovic-Cvijin I, Linehan JL, Bouladoux N, Merrill ED, Roy S, Cua DJ, Adams EJ, Bhandoola A, Scharschmidt TC, Aubé J, Fischbach MA, Belkaid Y. Constantinides MG, et al. Science. 2019 Oct 25;366(6464):eaax6624. doi: 10.1126/science.aax6624. Science. 2019. PMID: 31649166 Free PMC article.
Regulatory T Cells in Skin Facilitate Epithelial Stem Cell Differentiation.
Ali N, Zirak B, Rodriguez RS, Pauli ML, Truong HA, Lai K, Ahn R, Corbin K, Lowe MM, Scharschmidt TC, Taravati K, Tan MR, Ricardo-Gonzalez RR, Nosbaum A, Bertolini M, Liao W, Nestle FO, Paus R, Cotsarelis G, Abbas AK, Rosenblum MD. Ali N, et al. Cell. 2017 Jun 1;169(6):1119-1129.e11. doi: 10.1016/j.cell.2017.05.002. Epub 2017 May 25. Cell. 2017. PMID: 28552347 Free PMC article.
Skin Commensal Antigens: Taking the Road Less Traveled.
Dhariwala MO, Scharschmidt TC. Dhariwala MO, et al. Trends Immunol. 2018 Apr;39(4):259-261. doi: 10.1016/j.it.2018.02.001. Epub 2018 Feb 22. Trends Immunol. 2018. PMID: 29478772 Free PMC article.
Regulatory T cells use arginase 2 to enhance their metabolic fitness in tissues.
Lowe MM, Boothby I, Clancy S, Ahn RS, Liao W, Nguyen DN, Schumann K, Marson A, Mahuron KM, Kingsbury GA, Liu Z, Munoz Sandoval P, Rodriguez RS, Pauli ML, Taravati K, Arron ST, Neuhaus IM, Harris HW, Kim EA, Shin US, Krummel MF, Daud A, Scharschmidt TC, Rosenblum MD. Lowe MM, et al. JCI Insight. 2019 Dec 19;4(24):e129756. doi: 10.1172/jci.insight.129756. JCI Insight. 2019. PMID: 31852848 Free PMC article.