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Page 1
Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis.
Bobak CA, Abhimanyu, Natarajan H, Gandhi T, Grimm SL, Nishiguchi T, Koster K, Longlax SC, Dlamini Q, Kahari J, Mtetwa G, Cirillo JD, O'Malley J, Hill JE, Coarfa C, DiNardo AR. Bobak CA, et al. Aging (Albany NY). 2022 Mar 7;14(5):2174-2193. doi: 10.18632/aging.203936. Epub 2022 Mar 7. Aging (Albany NY). 2022. PMID: 35256539 Free PMC article.
Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes.
DiNardo AR, Gandhi T, Heyckendorf J, Grimm SL, Rajapakshe K, Nishiguchi T, Reimann M, Kirchner HL, Kahari J, Dlamini Q, Lange C, Goldmann T, Marwitz S; DZIF-TB cohort study group, Abhimanyu, Cirillo JD, Kaufmann SHE, Netea MG, van Crevel R, Mandalakas AM, Coarfa C. DiNardo AR, et al. Eur Respir J. 2022 Sep 15;60(3):2102263. doi: 10.1183/13993003.02263-2021. Print 2022 Sep. Eur Respir J. 2022. PMID: 35169026 Free PMC article.
Tuberculosis endotypes to guide stratified host-directed therapy.
DiNardo AR, Nishiguchi T, Grimm SL, Schlesinger LS, Graviss EA, Cirillo JD, Coarfa C, Mandalakas AM, Heyckendorf J, Kaufmann SHE, Lange C, Netea MG, Van Crevel R. DiNardo AR, et al. Med (N Y). 2021 Mar 12;2(3):217-232. doi: 10.1016/j.medj.2020.11.003. Epub 2021 Jan 16. Med (N Y). 2021. PMID: 34693385 Free PMC article.
Reversing Post-Infectious Epigenetic-Mediated Immune Suppression.
Abhimanyu, Ontiveros CO, Guerra-Resendez RS, Nishiguchi T, Ladki M, Hilton IB, Schlesinger LS, DiNardo AR. Abhimanyu, et al. Front Immunol. 2021 Jun 7;12:688132. doi: 10.3389/fimmu.2021.688132. eCollection 2021. Front Immunol. 2021. PMID: 34163486 Free PMC article. Review.
Trained immunity, tolerance, priming and differentiation: distinct immunological processes.
Divangahi M, Aaby P, Khader SA, Barreiro LB, Bekkering S, Chavakis T, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenvoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, Matarese G, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O'Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood ER, Schlitzer A, Schultze JL, Sieweke MH, Benn CS, Stunnenberg H, Sun J, van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG. Divangahi M, et al. Nat Immunol. 2021 Jan;22(1):2-6. doi: 10.1038/s41590-020-00845-6. Nat Immunol. 2021. PMID: 33293712 Free PMC article.