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3,063 results

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Page 1
K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution.
Suryo Rahmanto A, Blum CJ, Scalera C, Heidelberger JB, Mesitov M, Horn-Ghetko D, Gräf JF, Mikicic I, Hobrecht R, Orekhova A, Ostermaier M, Ebersberger S, Möckel MM, Krapoth N, Da Silva Fernandes N, Mizi A, Zhu Y, Chen JX, Choudhary C, Papantonis A, Ulrich HD, Schulman BA, König J, Beli P. Suryo Rahmanto A, et al. Mol Cell. 2023 Dec 7;83(23):4272-4289.e10. doi: 10.1016/j.molcel.2023.10.011. Epub 2023 Nov 10. Mol Cell. 2023. PMID: 37951215 Free article.
RPCs in the messenger RNA (mRNA) are recognized by the translating ribosomes, marked by atypical K6-linked ubiquitylation catalyzed by the RING-in-between-RING (RBR) E3 ligase RNF14, and subsequently resolved by the ubiquitin- and ATP-dependent unfoldase VCP. ...
RPCs in the messenger RNA (mRNA) are recognized by the translating ribosomes, marked by atypical K6-linked ubiquitylation catalyzed b …
The performance of the Japanese version of the K6 and K10 in the World Mental Health Survey Japan.
Furukawa TA, Kawakami N, Saitoh M, Ono Y, Nakane Y, Nakamura Y, Tachimori H, Iwata N, Uda H, Nakane H, Watanabe M, Naganuma Y, Hata Y, Kobayashi M, Miyake Y, Takeshima T, Kikkawa T. Furukawa TA, et al. Int J Methods Psychiatr Res. 2008;17(3):152-8. doi: 10.1002/mpr.257. Int J Methods Psychiatr Res. 2008. PMID: 18763695 Free PMC article.
Two new screening scales for psychological distress, the K6 and K10, have been developed using the item response theory and shown to outperform existing screeners in English. ...The Japanese versions of the K6 and K10 thus demonstrated screening performances essenti …
Two new screening scales for psychological distress, the K6 and K10, have been developed using the item response theory and shown to …
Pandemic Vibrio parahaemolyticus O3:K6 on the American continent.
Velazquez-Roman J, León-Sicairos N, de Jesus Hernández-Díaz L, Canizalez-Roman A. Velazquez-Roman J, et al. Front Cell Infect Microbiol. 2014 Jan 2;3:110. doi: 10.3389/fcimb.2013.00110. Front Cell Infect Microbiol. 2014. PMID: 24427744 Free PMC article. Review.
However, in February 1996, a unique serovar (O3:K6) of V. parahaemolyticus with specific genetic markers (tdh, toxRS/New and/or orf8) appeared abruptly in Kolkata, India. ...The emergence and worldwide dissemination of O3:K6 and other pandemic strains since 1996 hav …
However, in February 1996, a unique serovar (O3:K6) of V. parahaemolyticus with specific genetic markers (tdh, toxRS/New and/or orf8) …
Screening for serious mental illness in the general population.
Kessler RC, Barker PR, Colpe LJ, Epstein JF, Gfroerer JC, Hiripi E, Howes MJ, Normand SL, Manderscheid RW, Walters EE, Zaslavsky AM. Kessler RC, et al. Arch Gen Psychiatry. 2003 Feb;60(2):184-9. doi: 10.1001/archpsyc.60.2.184. Arch Gen Psychiatry. 2003. PMID: 12578436
However, neither the CIDI-SF nor the WHO-DAS improved prediction significantly over the K10 or K6 scales. The area under the receiver operating characteristic curve of SMI was 0.854 for K10 and 0.865 for K6. The most efficient screening scale, K6, had a sensi …
However, neither the CIDI-SF nor the WHO-DAS improved prediction significantly over the K10 or K6 scales. The area under the receiver …
Short screening scales to monitor population prevalences and trends in non-specific psychological distress.
Kessler RC, Andrews G, Colpe LJ, Hiripi E, Mroczek DK, Normand SL, Walters EE, Zaslavsky AM. Kessler RC, et al. Psychol Med. 2002 Aug;32(6):959-76. doi: 10.1017/s0033291702006074. Psychol Med. 2002. PMID: 12214795
The 10-question and six-question scales, which we refer to as the K10 and K6, were constructed from the reduced set of questions based on Item Response Theory models. ...Routine inclusion of either the K10 or K6 in clinical studies would create an important, and her …
The 10-question and six-question scales, which we refer to as the K10 and K6, were constructed from the reduced set of questions base …
K6-linked SUMOylation of BAF regulates nuclear integrity and DNA replication in mammalian cells.
Lin Q, Yu B, Wang X, Zhu S, Zhao G, Jia M, Huang F, Xu N, Ren H, Jiang Q, Zhang C. Lin Q, et al. Proc Natl Acad Sci U S A. 2020 May 12;117(19):10378-10387. doi: 10.1073/pnas.1912984117. Epub 2020 Apr 24. Proc Natl Acad Sci U S A. 2020. PMID: 32332162 Free PMC article.
K6-linked SUMOylation of BAF promotes binding and interaction with lamin A/C to regulate nuclear integrity. ...SENP1 and SENP2 catalyze the de-SUMOylation of BAF at K6. Disrupting the SUMOylation and de-SUMOylation cycle of BAF at K6 not only disturbs nuclear
K6-linked SUMOylation of BAF promotes binding and interaction with lamin A/C to regulate nuclear integrity. ...SENP1 and SENP2 cataly
[Progress in atypical ubiquitination via K6-linkages].
Wang Y, Huang S, Xu P, Li Y. Wang Y, et al. Sheng Wu Gong Cheng Xue Bao. 2022 Sep 25;38(9):3215-3227. doi: 10.13345/j.cjb.220041. Sheng Wu Gong Cheng Xue Bao. 2022. PMID: 36151794 Free article. Chinese.
However, it has been proved that atypical ubiquitin chains play a key role in intracellular regulation. K6 is an important atypical ubiquitin chain, which is similar to K48 chain and has a tight spatial structure. ...Due to the lack of specific antibodies and effective enr …
However, it has been proved that atypical ubiquitin chains play a key role in intracellular regulation. K6 is an important atypical u …
Global dissemination of Vibrio parahaemolyticus serotype O3:K6 and its serovariants.
Nair GB, Ramamurthy T, Bhattacharya SK, Dutta B, Takeda Y, Sack DA. Nair GB, et al. Clin Microbiol Rev. 2007 Jan;20(1):39-48. doi: 10.1128/CMR.00025-06. Clin Microbiol Rev. 2007. PMID: 17223622 Free PMC article. Review.
Analysis of the strains revealed that a unique serotype, O3:K6, not previously isolated during the surveillance in Calcutta accounted for 50 to 80% of the infections in the following months. ...Other serotypes, such as O4:K68, O1:K25, and O1:KUT (untypeable), that had mole …
Analysis of the strains revealed that a unique serotype, O3:K6, not previously isolated during the surveillance in Calcutta accounted …
The probiotic Lactobacillus kefiranofaciens K6 alleviates exercise and sleep deprivation-induced physiological dysregulation and neuropsychiatric disorders via modulation of inflammation, circadian rhythm, and stress response.
Chen CW, Wu LT, Chiu PH, Chen YP, Huang WC. Chen CW, et al. Int J Med Sci. 2025 Aug 11;22(14):3722-3736. doi: 10.7150/ijms.115387. eCollection 2025. Int J Med Sci. 2025. PMID: 40959574 Free PMC article.
Elevated injury indexes (CK and LDH) induced by SD combined with exercise training were also significantly reduced under K6 supplementation. In the liver and muscle, SD alone or combined with exercise led to inflammation (TNF-alpha) and dysregulated circadian gene expressi …
Elevated injury indexes (CK and LDH) induced by SD combined with exercise training were also significantly reduced under K6 supplemen …
Pathogen-defending deubiquitinase possesses distinct specificity towards K6-polyubiquitination.
Zhang Z, Das C. Zhang Z, et al. Trends Microbiol. 2023 May;31(5):423-425. doi: 10.1016/j.tim.2023.02.013. Epub 2023 Mar 6. Trends Microbiol. 2023. PMID: 36890008
Recently, Warren et al. revealed the structural basis of K6-polyubiquitination recognition by Legionella deubiquitinase LotA, while validating its potential as an enzymatic tool to study linkage-specific ubiquitination. ...
Recently, Warren et al. revealed the structural basis of K6-polyubiquitination recognition by Legionella deubiquitinase LotA, while v …
3,063 results