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The controversial world of sirtuins.
Dang W. Dang W. Drug Discov Today Technol. 2014 Jun;12:e9-e17. doi: 10.1016/j.ddtec.2012.08.003. Drug Discov Today Technol. 2014. PMID: 25027380 Free PMC article. Review.
Inactivation of yeast Isw2 chromatin remodeling enzyme mimics longevity effect of calorie restriction via induction of genotoxic stress response.
Dang W, Sutphin GL, Dorsey JA, Otte GL, Cao K, Perry RM, Wanat JJ, Saviolaki D, Murakami CJ, Tsuchiyama S, Robison B, Gregory BD, Vermeulen M, Shiekhattar R, Johnson FB, Kennedy BK, Kaeberlein M, Berger SL. Dang W, et al. Cell Metab. 2014 Jun 3;19(6):952-66. doi: 10.1016/j.cmet.2014.04.004. Epub 2014 May 8. Cell Metab. 2014. PMID: 24814484 Free PMC article.
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