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Innate immune mechanisms in ischemia/reperfusion.
Kaczorowski DJ, Tsung A, Billiar TR. Kaczorowski DJ, et al. Front Biosci (Elite Ed). 2009 Jun 1;1:91-8. Front Biosci (Elite Ed). 2009. PMID: 19482628 Review.
Mammalian DNA is an endogenous danger signal that stimulates local synthesis and release of complement factor B.
Kaczorowski DJ, Scott MJ, Pibris JP, Afrazi A, Nakao A, Edmonds RD, Kim S, Kwak JH, Liu Y, Fan J, Billiar TR. Kaczorowski DJ, et al. Mol Med. 2012 Jul 18;18(1):851-60. doi: 10.2119/molmed.2012.00011. Mol Med. 2012. PMID: 22526919 Free PMC article.
Pivotal advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms.
Kaczorowski DJ, Afrazi A, Scott MJ, Kwak JH, Gill R, Edmonds RD, Liu Y, Fan J, Billiar TR. Kaczorowski DJ, et al. J Leukoc Biol. 2010 Oct;88(4):609-18. doi: 10.1189/jlb.0809588. Epub 2010 Apr 22. J Leukoc Biol. 2010. PMID: 20413727 Free PMC article.
Increased expression and internalization of the endotoxin coreceptor CD14 in enterocytes occur as an early event in the development of experimental necrotizing enterocolitis.
Mollen KP, Gribar SC, Anand RJ, Kaczorowski DJ, Kohler JW, Branca MF, Dubowski TD, Sodhi CP, Hackam DJ. Mollen KP, et al. Among authors: kaczorowski dj. J Pediatr Surg. 2008 Jun;43(6):1175-81. doi: 10.1016/j.jpedsurg.2008.02.050. J Pediatr Surg. 2008. PMID: 18558203 Free PMC article.
Local exposure of bone components to injured soft tissue induces Toll-like receptor 4-dependent systemic inflammation with acute lung injury.
Kobbe P, Kaczorowski DJ, Vodovotz Y, Tzioupis CH, Mollen KP, Billiar TR, Pape HC. Kobbe P, et al. Among authors: kaczorowski dj. Shock. 2008 Dec;30(6):686-91. doi: 10.1097/SHK.0b013e31816f257e. Shock. 2008. PMID: 18461022
Early events in the recognition of danger signals after tissue injury.
Kaczorowski DJ, Mollen KP, Edmonds R, Billiar TR. Kaczorowski DJ, et al. J Leukoc Biol. 2008 Mar;83(3):546-52. doi: 10.1189/jlb.0607374. Epub 2007 Nov 21. J Leukoc Biol. 2008. PMID: 18032691 Review.
Systemic inflammation and remote organ injury following trauma require HMGB1.
Levy RM, Mollen KP, Prince JM, Kaczorowski DJ, Vallabhaneni R, Liu S, Tracey KJ, Lotze MT, Hackam DJ, Fink MP, Vodovotz Y, Billiar TR. Levy RM, et al. Among authors: kaczorowski dj. Am J Physiol Regul Integr Comp Physiol. 2007 Oct;293(4):R1538-44. doi: 10.1152/ajpregu.00272.2007. Epub 2007 Jul 25. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17652366
Systemic inflammation and end organ damage following trauma involves functional TLR4 signaling in both bone marrow-derived cells and parenchymal cells.
Mollen KP, Levy RM, Prince JM, Hoffman RA, Scott MJ, Kaczorowski DJ, Vallabhaneni R, Vodovotz Y, Billiar TR. Mollen KP, et al. Among authors: kaczorowski dj. J Leukoc Biol. 2008 Jan;83(1):80-8. doi: 10.1189/jlb.0407201. Epub 2007 Oct 9. J Leukoc Biol. 2008. PMID: 17925504
Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR. Kaczorowski DJ, et al. Transplantation. 2007 Nov 27;84(10):1279-87. doi: 10.1097/01.tp.0000287597.87571.17. Transplantation. 2007. PMID: 18049113
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