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Mediator and cohesin connect gene expression and chromatin architecture.
Kagey MH, Newman JJ, Bilodeau S, Zhan Y, Orlando DA, van Berkum NL, Ebmeier CC, Goossens J, Rahl PB, Levine SS, Taatjes DJ, Dekker J, Young RA. Kagey MH, et al. Nature. 2010 Sep 23;467(7314):430-5. doi: 10.1038/nature09380. Epub 2010 Aug 18. Nature. 2010. PMID: 20720539 Free PMC article.
The polycomb protein Pc2 is a SUMO E3.
Kagey MH, Melhuish TA, Wotton D. Kagey MH, et al. Cell. 2003 Apr 4;113(1):127-37. doi: 10.1016/s0092-8674(03)00159-4. Cell. 2003. PMID: 12679040 Free article.
Multiple activities contribute to Pc2 E3 function.
Kagey MH, Melhuish TA, Powers SE, Wotton D. Kagey MH, et al. EMBO J. 2005 Jan 12;24(1):108-19. doi: 10.1038/sj.emboj.7600506. Epub 2004 Dec 9. EMBO J. 2005. PMID: 15592428 Free PMC article.
Inhibition of CtBP1 activity by Akt-mediated phosphorylation.
Merrill JC, Kagey MH, Melhuish TA, Powers SE, Zerlanko BJ, Wotton D. Merrill JC, et al. Among authors: kagey mh. J Mol Biol. 2010 May 21;398(5):657-71. doi: 10.1016/j.jmb.2010.03.048. Epub 2010 Mar 31. J Mol Biol. 2010. PMID: 20361981 Free PMC article.
A Phase 1/2 multicenter trial of DKN-01 as monotherapy or in combination with docetaxel for the treatment of metastatic castration-resistant prostate cancer (mCRPC).
Wise DR, Pachynski RK, Denmeade SR, Aggarwal RR, Deng J, Febles VA, Balar AV, Economides MP, Loomis C, Selvaraj S, Haas M, Kagey MH, Newman W, Baum J, Troxel AB, Griglun S, Leis D, Yang N, Aranchiy V, Machado S, Waalkes E, Gargano G, Soamchand N, Puranik A, Chattopadhyay P, Fedal E, Deng FM, Ren Q, Chiriboga L, Melamed J, Sirard CA, Wong KK. Wise DR, et al. Among authors: kagey mh. Prostate Cancer Prostatic Dis. 2024 Feb 10. doi: 10.1038/s41391-024-00798-z. Online ahead of print. Prostate Cancer Prostatic Dis. 2024. PMID: 38341461
19 results