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Visualization of arrestin recruitment by a G-protein-coupled receptor.
Shukla AK, Westfield GH, Xiao K, Reis RI, Huang LY, Tripathi-Shukla P, Qian J, Li S, Blanc A, Oleskie AN, Dosey AM, Su M, Liang CR, Gu LL, Shan JM, Chen X, Hanna R, Choi M, Yao XJ, Klink BU, Kahsai AW, Sidhu SS, Koide S, Penczek PA, Kossiakoff AA, Woods VL Jr, Kobilka BK, Skiniotis G, Lefkowitz RJ. Shukla AK, et al. Among authors: kahsai aw. Nature. 2014 Aug 14;512(7513):218-222. doi: 10.1038/nature13430. Epub 2014 Jun 22. Nature. 2014. PMID: 25043026 Free PMC article.
Discovery of β2 Adrenergic Receptor Ligands Using Biosensor Fragment Screening of Tagged Wild-Type Receptor.
Aristotelous T, Ahn S, Shukla AK, Gawron S, Sassano MF, Kahsai AW, Wingler LM, Zhu X, Tripathi-Shukla P, Huang XP, Riley J, Besnard J, Read KD, Roth BL, Gilbert IH, Hopkins AL, Lefkowitz RJ, Navratilova I. Aristotelous T, et al. Among authors: kahsai aw. ACS Med Chem Lett. 2013 Oct 10;4(10):1005-1010. doi: 10.1021/ml400312j. Epub 2013 Sep 3. ACS Med Chem Lett. 2013. PMID: 24454993 Free PMC article.
GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling.
Thomsen ARB, Plouffe B, Cahill TJ 3rd, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, Bouvier M, Lefkowitz RJ. Thomsen ARB, et al. Among authors: kahsai aw. Cell. 2016 Aug 11;166(4):907-919. doi: 10.1016/j.cell.2016.07.004. Epub 2016 Aug 4. Cell. 2016. PMID: 27499021 Free PMC article.
29 results