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HIS-388, a novel orally active and long-acting 11β-hydroxysteroid dehydrogenase type 1 inhibitor, ameliorates insulin sensitivity and glucose intolerance in diet-induced obesity and nongenetic type 2 diabetic murine models.
Okazaki S, Takahashi T, Iwamura T, Nakaki J, Sekiya Y, Yagi M, Kumagai H, Sato M, Sakami S, Nitta A, Kawai K, Kainoh M. Okazaki S, et al. Among authors: kainoh m. J Pharmacol Exp Ther. 2014 Oct;351(1):181-9. doi: 10.1124/jpet.114.216556. Epub 2014 Aug 6. J Pharmacol Exp Ther. 2014. PMID: 25100752
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