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Toll-like receptors as adjuvant receptors.
Kaisho T, Akira S. Kaisho T, et al. Biochim Biophys Acta. 2002 Feb 13;1589(1):1-13. doi: 10.1016/s0167-4889(01)00182-3. Biochim Biophys Acta. 2002. PMID: 11909637 Review.
Transcriptional control of dendritic cell differentiation.
Sasaki I, Kaisho T. Sasaki I, et al. Curr Top Microbiol Immunol. 2014;381:257-78. doi: 10.1007/82_2014_378. Curr Top Microbiol Immunol. 2014. PMID: 24875951 Review.
Conservation of a chemokine system, XCR1 and its ligand, XCL1, between human and mice.
Yamazaki C, Miyamoto R, Hoshino K, Fukuda Y, Sasaki I, Saito M, Ishiguchi H, Yano T, Sugiyama T, Hemmi H, Tanaka T, Hamada E, Hirashima T, Amakawa R, Fukuhara S, Nomura S, Ito T, Kaisho T. Yamazaki C, et al. Biochem Biophys Res Commun. 2010 Jul 9;397(4):756-61. doi: 10.1016/j.bbrc.2010.06.029. Epub 2010 Jun 10. Biochem Biophys Res Commun. 2010. PMID: 20541533
NK and CD8(+) T cells increased XCL1 production upon activation. These expression patterns were conserved in human blood cells, including the BDCA3(+) DC subset. Thus, in human and mice, certain DC subsets should be chemotactic towards NK or activated CD8(+) T cells …
NK and CD8(+) T cells increased XCL1 production upon activation. These expression patterns were conserved in human blood cells, inclu …
Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection.
Honda K, Sakaguchi S, Nakajima C, Watanabe A, Yanai H, Matsumoto M, Ohteki T, Kaisho T, Takaoka A, Akira S, Seya T, Taniguchi T. Honda K, et al. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10872-7. doi: 10.1073/pnas.1934678100. Epub 2003 Sep 5. Proc Natl Acad Sci U S A. 2003. PMID: 12960379 Free PMC article.
We also show that the DCs stimulated in vivo by these agents can migrate into the T cell zone of the spleen but fail to mature without the IFN signal. ...
We also show that the DCs stimulated in vivo by these agents can migrate into the T cell zone of the spleen but fail to mature withou …
Regulation of dendritic cell function through toll-like receptors.
Kaisho T, Akira S. Kaisho T, et al. Curr Mol Med. 2003 Dec;3(8):759-71. doi: 10.2174/1566524033479366. Curr Mol Med. 2003. PMID: 14682496 Review.
DCs can incorporate pathogens, produce a variety of cytokines, maturate, and present pathogen-derived peptides to T cells, thereby inducing T cell activation and differentiation. ...
DCs can incorporate pathogens, produce a variety of cytokines, maturate, and present pathogen-derived peptides to T cells, thereby in …
Single-cell imaging of caspase-1 dynamics reveals an all-or-none inflammasome signaling response.
Liu T, Yamaguchi Y, Shirasaki Y, Shikada K, Yamagishi M, Hoshino K, Kaisho T, Takemoto K, Suzuki T, Kuranaga E, Ohara O, Miura M. Liu T, et al. Cell Rep. 2014 Aug 21;8(4):974-82. doi: 10.1016/j.celrep.2014.07.012. Epub 2014 Aug 7. Cell Rep. 2014. PMID: 25127135
A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.
Negishi H, Osawa T, Ogami K, Ouyang X, Sakaguchi S, Koshiba R, Yanai H, Seko Y, Shitara H, Bishop K, Yonekawa H, Tamura T, Kaisho T, Taya C, Taniguchi T, Honda K. Negishi H, et al. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20446-51. doi: 10.1073/pnas.0810372105. Epub 2008 Dec 11. Proc Natl Acad Sci U S A. 2008. PMID: 19074283 Free PMC article.
PDC-TREM, a plasmacytoid dendritic cell-specific receptor, is responsible for augmented production of type I interferon.
Watarai H, Sekine E, Inoue S, Nakagawa R, Kaisho T, Taniguchi M. Watarai H, et al. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2993-8. doi: 10.1073/pnas.0710351105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287072 Free PMC article.
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