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Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism.
Kazuki Y, Kobayashi K, Hirabayashi M, Abe S, Kajitani N, Kazuki K, Takehara S, Takiguchi M, Satoh D, Kuze J, Sakuma T, Kaneko T, Mashimo T, Osamura M, Hashimoto M, Wakatsuki R, Hirashima R, Fujiwara R, Deguchi T, Kurihara A, Tsukazaki Y, Senda N, Yamamoto T, Scheer N, Oshimura M. Kazuki Y, et al. Among authors: kajitani n. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3072-3081. doi: 10.1073/pnas.1808255116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718425 Free PMC article.
Complete genetic correction of ips cells from Duchenne muscular dystrophy.
Kazuki Y, Hiratsuka M, Takiguchi M, Osaki M, Kajitani N, Hoshiya H, Hiramatsu K, Yoshino T, Kazuki K, Ishihara C, Takehara S, Higaki K, Nakagawa M, Takahashi K, Yamanaka S, Oshimura M. Kazuki Y, et al. Among authors: kajitani n. Mol Ther. 2010 Feb;18(2):386-93. doi: 10.1038/mt.2009.274. Epub 2009 Dec 8. Mol Ther. 2010. PMID: 19997091 Free PMC article.
Refined human artificial chromosome vectors for gene therapy and animal transgenesis.
Kazuki Y, Hoshiya H, Takiguchi M, Abe S, Iida Y, Osaki M, Katoh M, Hiratsuka M, Shirayoshi Y, Hiramatsu K, Ueno E, Kajitani N, Yoshino T, Kazuki K, Ishihara C, Takehara S, Tsuji S, Ejima F, Toyoda A, Sakaki Y, Larionov V, Kouprina N, Oshimura M. Kazuki Y, et al. Among authors: kajitani n. Gene Ther. 2011 Apr;18(4):384-93. doi: 10.1038/gt.2010.147. Epub 2010 Nov 18. Gene Ther. 2011. PMID: 21085194 Free PMC article.
Trans-chromosomic mice containing a human CYP3A cluster for prediction of xenobiotic metabolism in humans.
Kazuki Y, Kobayashi K, Aueviriyavit S, Oshima T, Kuroiwa Y, Tsukazaki Y, Senda N, Kawakami H, Ohtsuki S, Abe S, Takiguchi M, Hoshiya H, Kajitani N, Takehara S, Kubo K, Terasaki T, Chiba K, Tomizuka K, Oshimura M. Kazuki Y, et al. Among authors: kajitani n. Hum Mol Genet. 2013 Feb 1;22(3):578-92. doi: 10.1093/hmg/dds468. Epub 2012 Nov 2. Hum Mol Genet. 2013. PMID: 23125282
Characterization of P-Glycoprotein Humanized Mice Generated by Chromosome Engineering Technology: Its Utility for Prediction of Drug Distribution to the Brain in Humans.
Yamasaki Y, Kobayashi K, Okuya F, Kajitani N, Kazuki K, Abe S, Takehara S, Ito S, Ogata S, Uemura T, Ohtsuki S, Minegishi G, Akita H, Chiba K, Oshimura M, Kazuki Y. Yamasaki Y, et al. Among authors: kajitani n. Drug Metab Dispos. 2018 Nov;46(11):1756-1766. doi: 10.1124/dmd.118.081216. Epub 2018 May 18. Drug Metab Dispos. 2018. PMID: 29777024
98 results