Kakefuda R - Search Results

1

Suppressive effect of an orally active MEK1/2 inhibitor in two different animal models for rheumatoid arthritis: a comparison with leflunomide.

Yamaguchi T, Kakefuda R, Tanimoto A, Watanabe Y, Tajima N. Yamaguchi T, et al. Among authors: kakefuda r. Inflamm Res. 2012 May;61(5):445-54. doi: 10.1007/s00011-011-0431-5. Epub 2012 Jan 14. Inflamm Res. 2012. PMID: 22245957

2

Antitumor activities of JTP-74057 (GSK1120212), a novel MEK1/2 inhibitor, on colorectal cancer cell lines in vitro and in vivo.

Yamaguchi T, Kakefuda R, Tajima N, Sowa Y, Sakai T. Yamaguchi T, et al. Among authors: kakefuda r. Int J Oncol. 2011 Jul;39(1):23-31. doi: 10.3892/ijo.2011.1015. Epub 2011 Apr 26. Int J Oncol. 2011. PMID: 21523318

3

Discovery of a Highly Potent and Selective MEK Inhibitor: GSK1120212 (JTP-74057 DMSO Solvate).

Abe H, Kikuchi S, Hayakawa K, Iida T, Nagahashi N, Maeda K, Sakamoto J, Matsumoto N, Miura T, Matsumura K, Seki N, Inaba T, Kawasaki H, Yamaguchi T, Kakefuda R, Nanayama T, Kurachi H, Hori Y, Yoshida T, Kakegawa J, Watanabe Y, Gilmartin AG, Richter MC, Moss KG, Laquerre SG. Abe H, et al. Among authors: kakefuda r. ACS Med Chem Lett. 2011 Feb 28;2(4):320-4. doi: 10.1021/ml200004g. eCollection 2011 Apr 14. ACS Med Chem Lett. 2011. PMID: 24900312 Free PMC article.

4

Pharmacological Properties of JTE-952, an Orally Available and Selective Colony Stimulating Factor 1 Receptor Kinase Inhibitor.

Uesato N, Miyagawa N, Inagaki K, Kakefuda R, Kitagawa Y, Matsuo Y, Yamaguchi T, Hata T, Ikegashira K, Matsushita M. Uesato N, et al. Among authors: kakefuda r. Biol Pharm Bull. 2020;43(2):325-333. doi: 10.1248/bpb.b19-00694. Biol Pharm Bull. 2020. PMID: 32009119 Free article.

5

JTE-952 Suppresses Bone Destruction in Collagen-Induced Arthritis in Mice by Inhibiting Colony Stimulating Factor 1 Receptor.

Uesato N, Inagaki K, Miyagawa N, Kitagawa Y, Kakefuda R, Matsuo Y, Yamaguchi T, Hata T, Ikegashira K, Matsushita M. Uesato N, et al. Among authors: kakefuda r. Biol Pharm Bull. 2020;43(12):1884-1892. doi: 10.1248/bpb.b20-00517. Biol Pharm Bull. 2020. PMID: 33268706 Free article.

6

Therapeutic Effect of Colony Stimulating Factor 1 Receptor Kinase Inhibitor, JTE-952, on Methotrexate-Refractory Pathology in a Rat Model of Rheumatoid Arthritis.

Uesato N, Kitagawa Y, Matsuo Y, Miyagawa N, Inagaki K, Kakefuda R, Yamaguchi T, Hata T, Ikegashira K, Matsushita M. Uesato N, et al. Among authors: kakefuda r. Biol Pharm Bull. 2023;46(9):1223-1230. doi: 10.1248/bpb.b23-00148. Biol Pharm Bull. 2023. PMID: 37661402 Free article.

7

A Novel TNF-α Converting Enzyme (TACE) Selective Inhibitor JTP-96193 Prevents Insulin Resistance in KK-A^y Type 2 Diabetic Mice and Diabetic Peripheral Neuropathy in Type 1 Diabetic Mice.

Maekawa M, Tadaki H, Tomimoto D, Okuma C, Sano R, Ishii Y, Katsuda Y, Yoshiuchi H, Kakefuda R, Ohta T, Sasase T. Maekawa M, et al. Among authors: kakefuda r. Biol Pharm Bull. 2019;42(11):1906-1912. doi: 10.1248/bpb.b19-00526. Biol Pharm Bull. 2019. PMID: 31685773 Free article.

8

Therapeutic effect of camostat mesilate on Duchenne muscular dystrophy in mdx mice.

Sawada H, Nagahiro K, Kikukawa Y, Ban S, Kakefuda R, Shiomi T, Yokosawa H. Sawada H, et al. Among authors: kakefuda r. Biol Pharm Bull. 2003 Jul;26(7):1025-7. doi: 10.1248/bpb.26.1025. Biol Pharm Bull. 2003. PMID: 12843632 Free article.

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