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Cdk2 knockout mice are viable.
Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Berthet C, et al. Among authors: kaldis p. Curr Biol. 2003 Oct 14;13(20):1775-85. doi: 10.1016/j.cub.2003.09.024. Curr Biol. 2003. PMID: 14561402
Human and yeast cdk-activating kinases (CAKs) display distinct substrate specificities.
Kaldis P, Russo AA, Chou HS, Pavletich NP, Solomon MJ. Kaldis P, et al. Mol Biol Cell. 1998 Sep;9(9):2545-60. doi: 10.1091/mbc.9.9.2545. Mol Biol Cell. 1998. PMID: 9725911 Free PMC article.
Transforming growth factor beta targeted inactivation of cyclin E:cyclin-dependent kinase 2 (Cdk2) complexes by inhibition of Cdk2 activating kinase activity.
Nagahara H, Ezhevsky SA, Vocero-Akbani AM, Kaldis P, Solomon MJ, Dowdy SF. Nagahara H, et al. Among authors: kaldis p. Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14961-6. doi: 10.1073/pnas.96.26.14961. Proc Natl Acad Sci U S A. 1999. PMID: 10611320 Free PMC article.
Analysis of CAK activities from human cells.
Kaldis P, Solomon MJ. Kaldis P, et al. Eur J Biochem. 2000 Jul;267(13):4213-21. doi: 10.1046/j.1432-1327.2000.01455.x. Eur J Biochem. 2000. PMID: 10866826
Cdk2 as a master of S phase entry: fact or fake?
Aleem E, Berthet C, Kaldis P. Aleem E, et al. Among authors: kaldis p. Cell Cycle. 2004 Jan;3(1):35-7. Cell Cycle. 2004. PMID: 14657662 Review.
Cell cycle-dependent phosphorylation of C/EBPbeta mediates oncogenic cooperativity between C/EBPbeta and H-RasV12.
Shuman JD, Sebastian T, Kaldis P, Copeland TD, Zhu S, Smart RC, Johnson PF. Shuman JD, et al. Among authors: kaldis p. Mol Cell Biol. 2004 Sep;24(17):7380-91. doi: 10.1128/MCB.24.17.7380-7391.2004. Mol Cell Biol. 2004. PMID: 15314150 Free PMC article.
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