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LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance.
Cunha LD, Yang M, Carter R, Guy C, Harris L, Crawford JC, Quarato G, Boada-Romero E, Kalkavan H, Johnson MDL, Natarajan S, Turnis ME, Finkelstein D, Opferman JT, Gawad C, Green DR. Cunha LD, et al. Among authors: kalkavan h. Cell. 2018 Oct 4;175(2):429-441.e16. doi: 10.1016/j.cell.2018.08.061. Epub 2018 Sep 20. Cell. 2018. PMID: 30245008 Free PMC article.
MOMP, cell suicide as a BCL-2 family business.
Kalkavan H, Green DR. Kalkavan H, et al. Cell Death Differ. 2018 Jan;25(1):46-55. doi: 10.1038/cdd.2017.179. Epub 2017 Oct 20. Cell Death Differ. 2018. PMID: 29053143 Free PMC article. Review.
Regulation of apoptosis by an intrinsically disordered region of Bcl-xL.
Follis AV, Llambi F, Kalkavan H, Yao Y, Phillips AH, Park CG, Marassi FM, Green DR, Kriwacki RW. Follis AV, et al. Among authors: kalkavan h. Nat Chem Biol. 2018 May;14(5):458-465. doi: 10.1038/s41589-018-0011-x. Epub 2018 Mar 5. Nat Chem Biol. 2018. PMID: 29507390 Free PMC article.
Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis.
Rodriguez DA, Quarato G, Liedmann S, Tummers B, Zhang T, Guy C, Crawford JC, Palacios G, Pelletier S, Kalkavan H, Shaw JJP, Fitzgerald P, Chen MJ, Balachandran S, Green DR. Rodriguez DA, et al. Among authors: kalkavan h. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2207240119. doi: 10.1073/pnas.2207240119. Epub 2022 Oct 3. Proc Natl Acad Sci U S A. 2022. PMID: 36191211 Free PMC article.
Sensitivity to anti-BRAF therapy: lost in translation.
Kalkavan H, Goding CR. Kalkavan H, et al. Pigment Cell Melanoma Res. 2015 Jan;28(1):4-5. doi: 10.1111/pcmr.12314. Epub 2014 Sep 30. Pigment Cell Melanoma Res. 2015. PMID: 25220342 No abstract available.
BRN2 suppresses apoptosis, reprograms DNA damage repair, and is associated with a high somatic mutation burden in melanoma.
Herbert K, Binet R, Lambert JP, Louphrasitthiphol P, Kalkavan H, Sesma-Sanz L, Robles-Espinoza CD, Sarkar S, Suer E, Andrews S, Chauhan J, Roberts ND, Middleton MR, Gingras AC, Masson JY, Larue L, Falletta P, Goding CR. Herbert K, et al. Among authors: kalkavan h. Genes Dev. 2019 Mar 1;33(5-6):310-332. doi: 10.1101/gad.314633.118. Epub 2019 Feb 25. Genes Dev. 2019. PMID: 30804224 Free PMC article.
Targeting the innate immunoreceptor RIG-I overcomes melanoma-intrinsic resistance to T cell immunotherapy.
Such L, Zhao F, Liu D, Thier B, Le-Trilling VTK, Sucker A, Coch C, Pieper N, Howe S, Bhat H, Kalkavan H, Ritter C, Brinkhaus R, Ugurel S, Köster J, Seifert U, Dittmer U, Schuler M, Lang KS, Kufer TA, Hartmann G, Becker JC, Horn S, Ferrone S, Liu D, Van Allen EM, Schadendorf D, Griewank K, Trilling M, Paschen A. Such L, et al. Among authors: kalkavan h. J Clin Invest. 2020 Aug 3;130(8):4266-4281. doi: 10.1172/JCI131572. J Clin Invest. 2020. PMID: 32427578 Free PMC article.
Spatiotemporally restricted arenavirus replication induces immune surveillance and type I interferon-dependent tumour regression.
Kalkavan H, Sharma P, Kasper S, Helfrich I, Pandyra AA, Gassa A, Virchow I, Flatz L, Brandenburg T, Namineni S, Heikenwalder M, Höchst B, Knolle PA, Wollmann G, von Laer D, Drexler I, Rathbun J, Cannon PM, Scheu S, Bauer J, Chauhan J, Häussinger D, Willimsky G, Löhning M, Schadendorf D, Brandau S, Schuler M, Lang PA, Lang KS. Kalkavan H, et al. Nat Commun. 2017 Mar 1;8:14447. doi: 10.1038/ncomms14447. Nat Commun. 2017. PMID: 28248314 Free PMC article.
15 results