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Page 1
A proposed eye irritation testing strategy to reduce and replace in vivo studies using Bottom-Up and Top-Down approaches.
Scott L, Eskes C, Hoffmann S, Adriaens E, Alepée N, Bufo M, Clothier R, Facchini D, Faller C, Guest R, Harbell J, Hartung T, Kamp H, Varlet BL, Meloni M, McNamee P, Osborne R, Pape W, Pfannenbecker U, Prinsen M, Seaman C, Spielmann H, Stokes W, Trouba K, Berghe CV, Goethem FV, Vassallo M, Vinardell P, Zuang V. Scott L, et al. Among authors: kamp h. Toxicol In Vitro. 2010 Feb;24(1):1-9. doi: 10.1016/j.tiv.2009.05.019. Epub 2009 May 31. Toxicol In Vitro. 2010. PMID: 19490935 Review.
Application of high throughput in vitro metabolomics for hepatotoxicity mode of action characterization and mechanistic-anchored point of departure derivation: a case study with nitrofurantoin.
Ramirez-Hincapie S, Birk B, Ternes P, Giri V, Zickgraf FM, Haake V, Herold M, Kamp H, Driemert P, Landsiedel R, Richling E, Funk-Weyer D, van Ravenzwaay B. Ramirez-Hincapie S, et al. Among authors: kamp h. Arch Toxicol. 2023 Nov;97(11):2903-2917. doi: 10.1007/s00204-023-03572-7. Epub 2023 Sep 4. Arch Toxicol. 2023. PMID: 37665362 Free PMC article.
Connecting Gut Microbial Diversity with Plasma Metabolome and Fecal Bile Acid Changes Induced by the Antibiotics Tobramycin and Colistin Sulfate.
Murali A, Giri V, Zickgraf FM, Ternes P, Cameron HJ, Sperber S, Haake V, Driemert P, Kamp H, Funk-Weyer D, Sturla SJ, Rietjens IMCM, van Ravenzwaay B. Murali A, et al. Among authors: kamp h. Chem Res Toxicol. 2023 Apr 17;36(4):598-616. doi: 10.1021/acs.chemrestox.2c00316. Epub 2023 Mar 27. Chem Res Toxicol. 2023. PMID: 36972423
Quality assurance of metabolomics.
Bouhifd M, Beger R, Flynn T, Guo L, Harris G, Hogberg H, Kaddurah-Daouk R, Kamp H, Kleensang A, Maertens A, Odwin-DaCosta S, Pamies D, Robertson D, Smirnova L, Sun J, Zhao L, Hartung T. Bouhifd M, et al. Among authors: kamp h. ALTEX. 2015;32(4):319-26. doi: 10.14573/altex.1509161. ALTEX. 2015. PMID: 26536290 Free PMC article.
Prediction of liver toxicity and mode of action using metabolomics in vitro in HepG2 cells.
Ramirez T, Strigun A, Verlohner A, Huener HA, Peter E, Herold M, Bordag N, Mellert W, Walk T, Spitzer M, Jiang X, Sperber S, Hofmann T, Hartung T, Kamp H, van Ravenzwaay B. Ramirez T, et al. Among authors: kamp h. Arch Toxicol. 2018 Feb;92(2):893-906. doi: 10.1007/s00204-017-2079-6. Epub 2017 Sep 30. Arch Toxicol. 2018. PMID: 28965233 Free PMC article.
Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project.
Escher SE, Kamp H, Bennekou SH, Bitsch A, Fisher C, Graepel R, Hengstler JG, Herzler M, Knight D, Leist M, Norinder U, Ouédraogo G, Pastor M, Stuard S, White A, Zdrazil B, van de Water B, Kroese D. Escher SE, et al. Among authors: kamp h. Arch Toxicol. 2019 Dec;93(12):3643-3667. doi: 10.1007/s00204-019-02591-7. Epub 2019 Nov 28. Arch Toxicol. 2019. PMID: 31781791
Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology.
Rovida C, Barton-Maclaren T, Benfenati E, Caloni F, Chandrasekera PC, Chesné C, Cronin MTD, De Knecht J, Dietrich DR, Escher SE, Fitzpatrick S, Flannery B, Herzler M, Hougaard Bennekou S, Hubesch B, Kamp H, Kisitu J, Kleinstreuer N, Kovarich S, Leist M, Maertens A, Nugent K, Pallocca G, Pastor M, Patlewicz G, Pavan M, Presgrave O, Smirnova L, Schwarz M, Yamada T, Hartung T. Rovida C, et al. Among authors: kamp h. ALTEX. 2020;37(4):579-606. doi: 10.14573/altex.1912181. Epub 2020 Apr 30. ALTEX. 2020. PMID: 32369604 Free PMC article.
The use of reconstructed human epidermis for skin absorption testing: Results of the validation study.
Schäfer-Korting M, Bock U, Diembeck W, Düsing HJ, Gamer A, Haltner-Ukomadu E, Hoffmann C, Kaca M, Kamp H, Kersen S, Kietzmann M, Korting HC, Krächter HU, Lehr CM, Liebsch M, Mehling A, Müller-Goymann C, Netzlaff F, Niedorf F, Rübbelke MK, Schäfer U, Schmidt E, Schreiber S, Spielmann H, Vuia A, Weimer M. Schäfer-Korting M, et al. Among authors: kamp h. Altern Lab Anim. 2008 May;36(2):161-87. doi: 10.1177/026119290803600207. Altern Lab Anim. 2008. PMID: 18522484
200 results