Kanaar R - Search Results

1

Suppression of retroviral infection by the RAD52 DNA repair protein.

Lau A, Kanaar R, Jackson SP, O'Connor MJ. Lau A, et al. Among authors: kanaar r. EMBO J. 2004 Aug 18;23(16):3421-9. doi: 10.1038/sj.emboj.7600348. Epub 2004 Aug 5. EMBO J. 2004. PMID: 15297876 Free PMC article.

2

Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.

Krawczyk PM, Eppink B, Essers J, Stap J, Rodermond H, Odijk H, Zelensky A, van Bree C, Stalpers LJ, Buist MR, Soullié T, Rens J, Verhagen HJ, O'Connor MJ, Franken NA, Ten Hagen TL, Kanaar R, Aten JA. Krawczyk PM, et al. Among authors: kanaar r. Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9851-6. doi: 10.1073/pnas.1101053108. Epub 2011 May 9. Proc Natl Acad Sci U S A. 2011. PMID: 21555554 Free PMC article.

3

CTG repeat instability and size variation timing in DNA repair-deficient mice.

Savouret C, Brisson E, Essers J, Kanaar R, Pastink A, te Riele H, Junien C, Gourdon G. Savouret C, et al. Among authors: kanaar r. EMBO J. 2003 May 1;22(9):2264-73. doi: 10.1093/emboj/cdg202. EMBO J. 2003. PMID: 12727892 Free PMC article.

4

Homologous and non-homologous recombination differentially affect DNA damage repair in mice.

Essers J, van Steeg H, de Wit J, Swagemakers SM, Vermeij M, Hoeijmakers JH, Kanaar R. Essers J, et al. Among authors: kanaar r. EMBO J. 2000 Apr 3;19(7):1703-10. doi: 10.1093/emboj/19.7.1703. EMBO J. 2000. PMID: 10747037 Free PMC article.

5

Nuclear dynamics of RAD52 group homologous recombination proteins in response to DNA damage.

Essers J, Houtsmuller AB, van Veelen L, Paulusma C, Nigg AL, Pastink A, Vermeulen W, Hoeijmakers JH, Kanaar R. Essers J, et al. Among authors: kanaar r. EMBO J. 2002 Apr 15;21(8):2030-7. doi: 10.1093/emboj/21.8.2030. EMBO J. 2002. PMID: 11953322 Free PMC article.

6

Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.

Naipal KA, Verkaik NS, Ameziane N, van Deurzen CH, Ter Brugge P, Meijers M, Sieuwerts AM, Martens JW, O'Connor MJ, Vrieling H, Hoeijmakers JH, Jonkers J, Kanaar R, de Winter JP, Vreeswijk MP, Jager A, van Gent DC. Naipal KA, et al. Among authors: kanaar r. Clin Cancer Res. 2014 Sep 15;20(18):4816-26. doi: 10.1158/1078-0432.CCR-14-0571. Epub 2014 Jun 24. Clin Cancer Res. 2014. PMID: 24963051

7

Mutation of the mouse Rad17 gene leads to embryonic lethality and reveals a role in DNA damage-dependent recombination.

Budzowska M, Jaspers I, Essers J, de Waard H, van Drunen E, Hanada K, Beverloo B, Hendriks RW, de Klein A, Kanaar R, Hoeijmakers JH, Maas A. Budzowska M, et al. Among authors: kanaar r. EMBO J. 2004 Sep 1;23(17):3548-58. doi: 10.1038/sj.emboj.7600353. Epub 2004 Aug 5. EMBO J. 2004. PMID: 15297881 Free PMC article.

8

The structure-specific endonuclease Mus81-Eme1 promotes conversion of interstrand DNA crosslinks into double-strands breaks.

Hanada K, Budzowska M, Modesti M, Maas A, Wyman C, Essers J, Kanaar R. Hanada K, et al. Among authors: kanaar r. EMBO J. 2006 Oct 18;25(20):4921-32. doi: 10.1038/sj.emboj.7601344. Epub 2006 Oct 12. EMBO J. 2006. PMID: 17036055 Free PMC article.

9

Quality control of DNA break metabolism: in the 'end', it's a good thing.

Kanaar R, Wyman C, Rothstein R. Kanaar R, et al. EMBO J. 2008 Feb 20;27(4):581-8. doi: 10.1038/emboj.2008.11. EMBO J. 2008. PMID: 18285819 Free PMC article. Review.

10

Rad52 and Ku bind to different DNA structures produced early in double-strand break repair.

Ristic D, Modesti M, Kanaar R, Wyman C. Ristic D, et al. Among authors: kanaar r. Nucleic Acids Res. 2003 Sep 15;31(18):5229-37. doi: 10.1093/nar/gkg729. Nucleic Acids Res. 2003. PMID: 12954758 Free PMC article.

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