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Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement.
Okazawa A, Kanai T, Watanabe M, Yamazaki M, Inoue N, Ikeda M, Kurimoto M, Ishii H, Hibi T. Okazawa A, et al. Among authors: kanai t. Am J Gastroenterol. 2002 Dec;97(12):3108-17. doi: 10.1111/j.1572-0241.2002.07107.x. Am J Gastroenterol. 2002. PMID: 12492197
ICOS costimulation in inflammatory bowel disease.
Kanai T, Totsuka T, Tezuka K, Watanabe M. Kanai T, et al. J Gastroenterol. 2002 Nov;37 Suppl 14:78-81. doi: 10.1007/BF03326419. J Gastroenterol. 2002. PMID: 12572871 Review.
Mucosal T cells as a target for treatment of IBD.
Watanabe M, Yamazaki M, Kanai T. Watanabe M, et al. Among authors: kanai t. J Gastroenterol. 2003 Mar;38 Suppl 15:48-50. J Gastroenterol. 2003. PMID: 12698871 Review.
1,496 results