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Matrix metalloproteinase inhibitor properties of tetracyclines: therapeutic potential in cardiovascular diseases.
Castro MM, Kandasamy AD, Youssef N, Schulz R. Castro MM, et al. Among authors: kandasamy ad. Pharmacol Res. 2011 Dec;64(6):551-60. doi: 10.1016/j.phrs.2011.05.005. Epub 2011 May 31. Pharmacol Res. 2011. PMID: 21689755 Review.
Doxycycline reduces cardiac matrix metalloproteinase-2 activity but does not ameliorate myocardial dysfunction during reperfusion in coronary artery bypass patients undergoing cardiopulmonary bypass.
Schulze CJ, Castro MM, Kandasamy AD, Cena J, Bryden C, Wang SH, Koshal A, Tsuyuki RT, Finegan BA, Schulz R. Schulze CJ, et al. Among authors: kandasamy ad. Crit Care Med. 2013 Nov;41(11):2512-20. doi: 10.1097/CCM.0b013e318292373c. Crit Care Med. 2013. PMID: 23928836 Clinical Trial.
Hydrogen peroxide-induced necrotic cell death in cardiomyocytes is independent of matrix metalloproteinase-2.
Ali MA, Kandasamy AD, Fan X, Schulz R. Ali MA, et al. Among authors: kandasamy ad. Toxicol In Vitro. 2013 Sep;27(6):1686-92. doi: 10.1016/j.tiv.2013.04.013. Epub 2013 May 7. Toxicol In Vitro. 2013. PMID: 23665313
Mechanisms of cytosolic targeting of matrix metalloproteinase-2.
Ali MA, Chow AK, Kandasamy AD, Fan X, West LJ, Crawford BD, Simmen T, Schulz R. Ali MA, et al. Among authors: kandasamy ad. J Cell Physiol. 2012 Oct;227(10):3397-404. doi: 10.1002/jcp.24040. J Cell Physiol. 2012. PMID: 22212960
Matrix metalloproteinase-2 and myocardial oxidative stress injury: beyond the matrix.
Kandasamy AD, Chow AK, Ali MA, Schulz R. Kandasamy AD, et al. Cardiovasc Res. 2010 Feb 1;85(3):413-23. doi: 10.1093/cvr/cvp268. Epub 2009 Aug 4. Cardiovasc Res. 2010. PMID: 19656780 Review.
Glycogen synthase kinase-3beta is activated by matrix metalloproteinase-2 mediated proteolysis in cardiomyoblasts.
Kandasamy AD, Schulz R. Kandasamy AD, et al. Cardiovasc Res. 2009 Sep 1;83(4):698-706. doi: 10.1093/cvr/cvp175. Epub 2009 Jun 3. Cardiovasc Res. 2009. PMID: 19493954
Inhibition of matrix metalloproteinase-2 by PARP inhibitors.
Nicolescu AC, Holt A, Kandasamy AD, Pacher P, Schulz R. Nicolescu AC, et al. Among authors: kandasamy ad. Biochem Biophys Res Commun. 2009 Oct 2;387(4):646-50. doi: 10.1016/j.bbrc.2009.07.080. Epub 2009 Jul 18. Biochem Biophys Res Commun. 2009. PMID: 19619515 Free PMC article.
Adiponectin gene therapy ameliorates high-fat, high-sucrose diet-induced metabolic perturbations in mice.
Kandasamy AD, Sung MM, Boisvenue JJ, Barr AJ, Dyck JR. Kandasamy AD, et al. Nutr Diabetes. 2012 Sep 10;2(9):e45. doi: 10.1038/nutd.2012.18. Nutr Diabetes. 2012. PMID: 23446660 Free PMC article.
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