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Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth.
Bruchard M, Mignot G, Derangère V, Chalmin F, Chevriaux A, Végran F, Boireau W, Simon B, Ryffel B, Connat JL, Kanellopoulos J, Martin F, Rébé C, Apetoh L, Ghiringhelli F. Bruchard M, et al. Among authors: kanellopoulos j. Nat Med. 2013 Jan;19(1):57-64. doi: 10.1038/nm.2999. Epub 2012 Dec 2. Nat Med. 2013. PMID: 23202296
Is the inflammasome relevant for epithelial cell function?
Santana PT, Martel J, Lai HC, Perfettini JL, Kanellopoulos JM, Young JD, Coutinho-Silva R, Ojcius DM. Santana PT, et al. Among authors: kanellopoulos jm. Microbes Infect. 2016 Feb;18(2):93-101. doi: 10.1016/j.micinf.2015.10.007. Epub 2015 Nov 10. Microbes Infect. 2016. PMID: 26546965 Review.
Public and private V beta T cell receptor repertoires against hen egg white lysozyme (HEL) in nontransgenic versus HEL transgenic mice.
Cibotti R, Cabaniols JP, Pannetier C, Delarbre C, Vergnon I, Kanellopoulos JM, Kourilsky P. Cibotti R, et al. Among authors: kanellopoulos jm. J Exp Med. 1994 Sep 1;180(3):861-72. doi: 10.1084/jem.180.3.861. J Exp Med. 1994. PMID: 8064237 Free PMC article.
We found that a V beta 8.2-D beta 1-J beta 1.5 rearrangement is found in response to HEL in all nontransgenic mice, whereas this V beta-restricted response is absent in HEL-low transgenic animals. ...Instead, each transgenic animal uses a different set of V beta-J b …
We found that a V beta 8.2-D beta 1-J beta 1.5 rearrangement is found in response to HEL in all nontransgenic mice, whereas this V be …
Interleukin 4-producing CD4 T cells arise from different precursors depending on the conditions of antigen exposure in vivo.
Foucras G, Gapin L, Coureau C, Kanellopoulos JM, Guéry JC. Foucras G, et al. Among authors: kanellopoulos jm. J Exp Med. 2000 Feb 21;191(4):683-94. doi: 10.1084/jem.191.4.683. J Exp Med. 2000. PMID: 10684860 Free PMC article.
To analyze the origin of effector T cells in this model, we designed a competitive polymerase chain reaction-based approach to track public BV-J rearrangement expressed by CD4 T cells specific for hen egg white lysozyme (HEL) in BALB/c mice. ...
To analyze the origin of effector T cells in this model, we designed a competitive polymerase chain reaction-based approach to track public …
Most alpha/beta T cell receptor diversity is due to terminal deoxynucleotidyl transferase.
Cabaniols JP, Fazilleau N, Casrouge A, Kourilsky P, Kanellopoulos JM. Cabaniols JP, et al. Among authors: kanellopoulos jm. J Exp Med. 2001 Nov 5;194(9):1385-90. doi: 10.1084/jem.194.9.1385. J Exp Med. 2001. PMID: 11696602 Free PMC article.
Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Génin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, André F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L. Ghiringhelli F, et al. Among authors: kanellopoulos j. Nat Med. 2009 Oct;15(10):1170-8. doi: 10.1038/nm.2028. Epub 2009 Sep 20. Nat Med. 2009. PMID: 19767732
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection.
Séror C, Melki MT, Subra F, Raza SQ, Bras M, Saïdi H, Nardacci R, Voisin L, Paoletti A, Law F, Martins I, Amendola A, Abdul-Sater AA, Ciccosanti F, Delelis O, Niedergang F, Thierry S, Said-Sadier N, Lamaze C, Métivier D, Estaquier J, Fimia GM, Falasca L, Casetti R, Modjtahedi N, Kanellopoulos J, Mouscadet JF, Ojcius DM, Piacentini M, Gougeon ML, Kroemer G, Perfettini JL. Séror C, et al. Among authors: kanellopoulos j. J Exp Med. 2011 Aug 29;208(9):1823-34. doi: 10.1084/jem.20101805. Epub 2011 Aug 22. J Exp Med. 2011. PMID: 21859844 Free PMC article.
P2 receptors and immunity.
Rayah A, Kanellopoulos JM, Di Virgilio F. Rayah A, et al. Among authors: kanellopoulos jm. Microbes Infect. 2012 Nov;14(14):1254-62. doi: 10.1016/j.micinf.2012.07.006. Epub 2012 Aug 13. Microbes Infect. 2012. PMID: 22909902 Free PMC article. Review.
IL-33 enhances lipopolysaccharide-induced inflammatory cytokine production from mouse macrophages by regulating lipopolysaccharide receptor complex.
Espinassous Q, Garcia-de-Paco E, Garcia-Verdugo I, Synguelakis M, von Aulock S, Sallenave JM, McKenzie AN, Kanellopoulos J. Espinassous Q, et al. Among authors: kanellopoulos j. J Immunol. 2009 Jul 15;183(2):1446-55. doi: 10.4049/jimmunol.0803067. Epub 2009 Jun 24. J Immunol. 2009. PMID: 19553541
P2Z/P2X7 receptor-dependent apoptosis of dendritic cells.
Coutinho-Silva R, Persechini PM, Bisaggio RD, Perfettini JL, Neto AC, Kanellopoulos JM, Motta-Ly I, Dautry-Varsat A, Ojcius DM. Coutinho-Silva R, et al. Among authors: kanellopoulos jm. Am J Physiol. 1999 May;276(5):C1139-47. doi: 10.1152/ajpcell.1999.276.5.C1139. Am J Physiol. 1999. PMID: 10329963
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