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The sirtuin SIRT6 regulates lifespan in male mice.
Kanfi Y, Naiman S, Amir G, Peshti V, Zinman G, Nahum L, Bar-Joseph Z, Cohen HY. Kanfi Y, et al. Nature. 2012 Feb 22;483(7388):218-21. doi: 10.1038/nature10815. Nature. 2012. PMID: 22367546
Restoration of energy homeostasis by SIRT6 extends healthy lifespan.
Roichman A, Elhanati S, Aon MA, Abramovich I, Di Francesco A, Shahar Y, Avivi MY, Shurgi M, Rubinstein A, Wiesner Y, Shuchami A, Petrover Z, Lebenthal-Loinger I, Yaron O, Lyashkov A, Ubaida-Mohien C, Kanfi Y, Lerrer B, Fernández-Marcos PJ, Serrano M, Gottlieb E, de Cabo R, Cohen HY. Roichman A, et al. Among authors: kanfi y. Nat Commun. 2021 May 28;12(1):3208. doi: 10.1038/s41467-021-23545-7. Nat Commun. 2021. PMID: 34050173 Free PMC article.
Sirtuins as regulators of mammalian aging.
Naiman S, Kanfi Y, Cohen HY. Naiman S, et al. Among authors: kanfi y. Aging (Albany NY). 2012 Aug;4(8):521-2. doi: 10.18632/aging.100478. Aging (Albany NY). 2012. PMID: 22915706 Free PMC article. No abstract available.
SIRT6 Overexpression Improves Various Aspects of Mouse Healthspan.
Roichman A, Kanfi Y, Glazz R, Naiman S, Amit U, Landa N, Tinman S, Stein I, Pikarsky E, Leor J, Cohen HY. Roichman A, et al. Among authors: kanfi y. J Gerontol A Biol Sci Med Sci. 2017 May 1;72(5):603-615. doi: 10.1093/gerona/glw152. J Gerontol A Biol Sci Med Sci. 2017. PMID: 27519885
Characterization of physiological defects in adult SIRT6-/- mice.
Peshti V, Obolensky A, Nahum L, Kanfi Y, Rathaus M, Avraham M, Tinman S, Alt FW, Banin E, Cohen HY. Peshti V, et al. Among authors: kanfi y. PLoS One. 2017 Apr 27;12(4):e0176371. doi: 10.1371/journal.pone.0176371. eCollection 2017. PLoS One. 2017. PMID: 28448551 Free PMC article.
Regulation of SIRT6 protein levels by nutrient availability.
Kanfi Y, Shalman R, Peshti V, Pilosof SN, Gozlan YM, Pearson KJ, Lerrer B, Moazed D, Marine JC, de Cabo R, Cohen HY. Kanfi Y, et al. FEBS Lett. 2008 Mar 5;582(5):543-8. doi: 10.1016/j.febslet.2008.01.019. Epub 2008 Jan 31. FEBS Lett. 2008. PMID: 18242175 Free PMC article.
Regulation of SIRT1 protein levels by nutrient availability.
Kanfi Y, Peshti V, Gozlan YM, Rathaus M, Gil R, Cohen HY. Kanfi Y, et al. FEBS Lett. 2008 Jul 9;582(16):2417-23. doi: 10.1016/j.febslet.2008.06.005. Epub 2008 Jun 9. FEBS Lett. 2008. PMID: 18544345 Free article.
SIRT6 exhibits nucleosome-dependent deacetylase activity.
Gil R, Barth S, Kanfi Y, Cohen HY. Gil R, et al. Among authors: kanfi y. Nucleic Acids Res. 2013 Oct;41(18):8537-45. doi: 10.1093/nar/gkt642. Epub 2013 Jul 26. Nucleic Acids Res. 2013. PMID: 23892288 Free PMC article.
Multiple regulatory layers of SREBP1/2 by SIRT6.
Elhanati S, Kanfi Y, Varvak A, Roichman A, Carmel-Gross I, Barth S, Gibor G, Cohen HY. Elhanati S, et al. Among authors: kanfi y. Cell Rep. 2013 Sep 12;4(5):905-12. doi: 10.1016/j.celrep.2013.08.006. Epub 2013 Sep 5. Cell Rep. 2013. PMID: 24012758 Free article.
19 results