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Small molecule SWELL1 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes.
Gunasekar SK, Xie L, Kumar A, Hong J, Chheda PR, Kang C, Kern DM, My-Ta C, Maurer J, Heebink J, Gerber EE, Grzesik WJ, Elliot-Hudson M, Zhang Y, Key P, Kulkarni CA, Beals JW, Smith GI, Samuel I, Smith JK, Nau P, Imai Y, Sheldon RD, Taylor EB, Lerner DJ, Norris AW, Klein S, Brohawn SG, Kerns R, Sah R. Gunasekar SK, et al. Among authors: kang c. Nat Commun. 2022 Feb 10;13(1):784. doi: 10.1038/s41467-022-28435-0. Nat Commun. 2022. PMID: 35145074 Free PMC article.
The SWELL1-LRRC8 complex regulates endothelial AKT-eNOS signaling and vascular function.
Alghanem AF, Abello J, Maurer JM, Kumar A, Ta CM, Gunasekar SK, Fatima U, Kang C, Xie L, Adeola O, Riker M, Elliot-Hudson M, Minerath RA, Grueter CE, Mullins RF, Stratman AN, Sah R. Alghanem AF, et al. Among authors: kang c. Elife. 2021 Feb 25;10:e61313. doi: 10.7554/eLife.61313. Elife. 2021. PMID: 33629656 Free PMC article.
Mechanism and effects of pulsatile GABA secretion from cytosolic pools in the human beta cell.
Menegaz D, Hagan DW, Almaça J, Cianciaruso C, Rodriguez-Diaz R, Molina J, Dolan RM, Becker MW, Schwalie PC, Nano R, Lebreton F, Kang C, Sah R, Gaisano HY, Berggren PO, Baekkeskov S, Caicedo A, Phelps EA. Menegaz D, et al. Among authors: kang c. Nat Metab. 2019 Nov;1(11):1110-1126. doi: 10.1038/s42255-019-0135-7. Epub 2019 Nov 15. Nat Metab. 2019. PMID: 32432213 Free PMC article.
Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria.
Mishra A, Liu S, Promes J, Harata M, Sivitz W, Fink B, Bhardwaj G, O'Neill BT, Kang C, Sah R, Strack S, Stephens S, King T, Jackson L, Greenberg AS, Anokye-Danso F, Ahima RS, Ankrum J, Imai Y. Mishra A, et al. Among authors: kang c. JCI Insight. 2021 May 10;6(9):e144341. doi: 10.1172/jci.insight.144341. JCI Insight. 2021. PMID: 33784258 Free PMC article.
6,211 results