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Up-regulation of aldose reductase expression mediated by phosphatidylinositol 3-kinase/Akt and Nrf2 is involved in the protective effect of curcumin against oxidative damage.
Kang ES, Woo IS, Kim HJ, Eun SY, Paek KS, Kim HJ, Chang KC, Lee JH, Lee HT, Kim JH, Nishinaka T, Yabe-Nishimura C, Seo HG. Kang ES, et al. Free Radic Biol Med. 2007 Aug 15;43(4):535-45. doi: 10.1016/j.freeradbiomed.2007.05.006. Epub 2007 May 16. Free Radic Biol Med. 2007. PMID: 17640564
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